皮肤癣菌与过敏性疾病的相关性研究进展  

Advances in the study of dermatophytes and allergic diseases

作　　者：刘文韬 周昕 冯佩英[1,2] LIU Wentao;ZHOU Xin;FENG Peiying(Department of Dermatology and Cosmetic Surgery,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China;Department of Allergy,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China;RadboudUMC/CWZ Center of Expertise for Mycology,Nijmegen 6525GA,The Netherlands)

机构地区：[1]中山大学附属第三医院皮肤与整形美容科,广东广州510630 [2]中山大学附属第三医院过敏科,广东广州510630 [3]奈梅亨大学医学中心,荷兰奈梅亨6525GA

出　　处：《新医学》2024年第10期828-834,共7页Journal of New Medicine

基　　金：广东省自然科学基金(2020A1515011183)。

摘　　要：皮肤癣菌病分布于世界各地,全球患病率高达20%~25%;而过敏性疾病在全球普通人群中患病率也高达10%~45%。近年来,皮肤癣菌与过敏性鼻炎、特应性皮炎、哮喘等过敏性疾病相关性的研究陆续被报道,而皮肤癣菌与过敏性疾病的相关性并未受到广泛关注。文章对真菌过敏原研究现状、皮肤癣菌与过敏性疾病的相关性报道以及皮肤癣菌导致过敏性疾病的可能机制等进行综述,为临床诊疗皮肤癣菌病与过敏性疾病提供参考。Dermatophytosis is distributed worldwide,with a global prevalence of 20%-25%,while allergic diseases have a high prevalence of 10%-45%in the global population.In recent years,research on the correlation between dermatophytosis and allergic diseases such as allergic rhinitis,atopic dermatitis,and asthma has been reported successively,highlighting a previously overlooked relationship between dermatophytes and allergic diseases.This review summarizes the research progress on fungal allergens,the correlation between dermatophytosis and allergic diseases,as well as the mechanisms of interaction,aiming to provide insights for the clinical diagnosis and treatment of dermatophytosis and allergic diseases.

关 键 词：皮肤癣菌 皮肤癣菌病 真菌过敏原 过敏性疾病 机制 

分 类 号：R756[医药卫生—皮肤病学与性病学] R593.1[医药卫生—临床医学]