Amplification editing empowers in situ large-scale DNA duplication  

作　　者：Yali Cui Yi Wu Yingjin Yuan 

机构地区：[1]Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering(Ministry of Education),School of Chemical Engineering and Technology,Tianjin University,Tianjin 300000,China [2]Frontiers Research Institute for Synthetic Biology,Tianjin University,Tianjin 300000,China

出　　处：《The Innovation》2024年第6期33-34,共2页创新（英文）

基　　金：supported by the National Key R&D Programof China(2019YFA0903800 and 2021YFC2102500);the National Natural Science Foundation of China(32471483);the Natural Science Foundation of Tianjin(23JCYBJC00220).

摘　　要：Repetitive sequences in genomes play crucial biological roles involved in maintaining chromosome structure or the development of diseases.Modeling naturally occurring large-scale repetitive sequences will facilitate the exploration of their functions and elucidate their underlying mechanisms.However,constructing programmable large-scale repetitive sequences on chromosomes remains a challenge.

关 键 词：mechanisms. SEQUENCES CONSTRUCTING 

分 类 号：Q78[生物学—分子生物学]