Lipidome and proteome analyses provide insights into Mariana Trench Snailfish(Pseudoliparis swirei)adaptation to the hadal zone  

作　　者：Han Xu Chengchi Fang Cheng Wang Xiaoni Gan Shunping He 

机构地区：[1]Institute of Deep-Sea Science and Engineering,Chinese Academy of Sciences,Sanya,572000,China [2]State Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture,Institute of Hydrobiology,Chinese Academy of Sciences,Wuhan,430072,China [3]University of Chinese Academy of Sciences,Beijing,China

出　　处：《Water Biology and Security》2024年第4期143-150,共8页水生生物与安全（英文）

基　　金：supported by The Strategic Priority Research Program of the Chinese Academy of Sciences(XDB42030000);The National Key Research and Development Program of China(2022YFC2805400,2016YFC0304905);The National Natural Science Foundation of China(42330405);The National Natural Science Foundation of China(41876179).

摘　　要：The hadal zone environment,characterized by extreme hydrostatic pressure,low temperatures,and limited food availability,presents substantial survival challenges for deep-sea fish species.In this study,we captured five deepsea fish species(Bathysaurus mollis,Coryphaenoides rudis,Ilyophis sp.,I.brunneus and Pseudoliparis swirei)from the Mariana Trench at depths ranging from 2027 to 7125 m,by employing China's“Exploration I and Exploration II”.By combining lipidomic and proteomic analyses,we aimed to explore the genetic basis of adaptive evolution to the hadal zone in fish.The results indicate several key findings:(1)P.swirei(Mariana hadal snailfish,MHS)may enhance energy storage and utilization during prolonged fasting periods by significantly increasing liver tissue levels of cholesterol ester(CE),ether-linked triacylglycerol(TG-O),coenzyme Q(CoQ),and ATPase content;(2)MHS could maintain membrane fluidity under high pressure by increasing the proportion of unsaturated fatty acids while reducing levels of cholesterol and phosphatidylethanolamine(PE)content.(3)The regulation of lipid types and ratios could increase the risk of lipid peroxidation.To counter oxidative stress,MHS likely elevates monounsaturated fatty acid content and enhances antioxidants such as transferrin and heat shock proteins.Overall,this study provides new insights into the adaptive mechanisms of MHS to deep-sea conditions through the lipidome and proteome analyses,thus broadening our understanding of its resilience in the hadal zone.

关 键 词：Deep sea FISH Hadal zone LIPIDOME PROTEOME 

分 类 号：Q95[生物学—动物学]