机构地区:[1]南京中医药大学张家港附属医院妇科,江苏张家港215600 [2]南京中医药大学张家港附属医院生殖科,江苏张家港215600
出 处:《妇儿健康导刊》2024年第21期31-35,共5页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
基 金:江苏省科技项目社会发展--面上项目(BE2023734);江苏省自然科学基金(BK20221266);江苏省苏州市重大疾病多中心临床研究项目(DZXYJ202311);江苏省苏州市科技计划项目(SKY2022070;SKYD2022010;SLT2022012)。
摘 要:目的探讨针刺联合低碳水化合物膳食在超重型多囊卵巢综合征(PCOS)患者综合管理中的应用效果。方法选取2020年1月至2023年6月在南京中医药大学张家港附属医院就诊的96例超重型PCOS患者为研究对象,采用随机数字表法分为两组,各48例。对照组予以低碳水化合物膳食指导,研究组在其基础上联合针刺,比较两组治疗前后性激素、体重、体重指数、腰臀比、空腹血糖、空腹胰岛素及胰岛素抵抗指数、中医证候积分情况。结果治疗3个月后研究组睾酮水平低于对照组(P<0.05)。两组组内不同时间点体重、体重指数、腰臀比比较,差异有统计学意义(P<0.05);研究组治疗3个月后、治疗后6个月体重、体重指数低于对照组(P<0.05)。两组组内不同时间点空腹血糖、空腹胰岛素、胰岛素抵抗指数比较,差异有统计学意义(P<0.05);研究组治疗3个月后、治疗后6个月空腹胰岛素、胰岛素抵抗指数低于对照组(P<0.05)。研究组治疗3个月后中医证候积分较对照组更低(P<0.05)。结论针刺联合低碳水化合物膳食可调节超重型PCOS患者的血清性激素水平,降低体重指数,纠正糖代谢紊乱,改善中医证候。Objective To explore the application effect of acupuncture combined with low carbohydrate diet in the comprehensive management of patients with overweight type polycystic ovary syndrome(PCOS).Methods A total of 96 patients with overweight type PCOS who were treated in Zhangjiagang Affiliated Hospital of Nanjing University of Chinese Medicine from January 2020 to June 2023 were selected as the research objects,and they were divided into two groups by random number table method,with 48 cases in each group.The control group was given low carbohydrate diet guidance,and the study group was given acupuncture on the basis of the control group.The sex hormones,body weight,body mass index,waist-to-hip ratio,fasting blood glucose,fasting insulin,homeostasis model assessment of insulin resistance index,and traditional Chinese medicine syndrome score before and after treatment were compared between the two groups.Results After 3 months of treatment,the level of testosterone in the study group was lower than that in the control group(P<0.05).There were statistically significant differences in body weight,body mass index,and waist-to-hip ratio between within the two groups at different time points(P<0.05).The body weight and body mass index of the study group after 3 months of treatment and 6 months after treatment were lower than those of the control group(P<0.05).There were significant differences in fasting blood glucose,fasting insulin,and homeostasis model assessment of insulin resistance index within the two groups at different time points(P<0.05).After 3 months of treatment and 6 months after treatment,fasting insulin and homeostasis model assessment of insulin resistance index in the study group were lower than those in the control group(P<0.05).After 3 months of treatment,the traditional Chinese medicine syndrome score of the study group was lower than that of the control group(P<0.05).Conclusion Acupuncture combined with low carbohydrate diet can regulate serum sex hormone levels,reduce body mass index,correct glucos
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