臭氧联合利多卡因痛点注射对慢性腰肌劳损患者疼痛及血清炎性因子水平的影响  

Effects of ozone combined with lidocaine pain point injection on pain and serum inflammatory factor lev-els in patients with chronic lumbar muscle strain

作　　者：龚晓霞 赵刚建 袁雯雯 Gong Xiaoxia;Zhao Gangjian;Yuan Wenwen(Department of Orthopedics and Traumatology,Zhengzhou Hospital of Traditional Chinese Medicine,Zhengzhou,Henan 450016,China;Department of Osteoarthritis,Zhengzhou Hospital of Traditional Chinese Medicine,Zhengzhou,Henan 450016,China;Department of Rehabilitation,Zhengzhou Hospital of Traditional Chinese Medicine,Zhengzhou,Henan 450016,China)

机构地区：[1]郑州中医骨伤病医院骨伤科,河南郑州450016 [2]郑州中医骨伤病医院骨关节科,河南郑州450016 [3]郑州中医骨伤病医院康复科,河南郑州450016

出　　处：《中国药物与临床》2024年第22期1478-1482,共5页Chinese Remedies & Clinics

摘　　要：目的探究慢性腰肌劳损患者应用臭氧联合利多卡因痛点注射的临床效果。方法按治疗方法将2021年7月至2023年8月郑州中医骨伤病医院收治的80例慢性腰肌劳损患者分为研究组(40例)及对照组(40例)。对照组采用利多卡因痛点注射治疗,在对照组治疗基础上研究组联合臭氧治疗,2组均治疗1个疗程。对比2组临床疗效、疼痛视觉模拟评分(VAS)、腰椎功能(JOA)及腰椎功能障碍指数(ODI)、炎性因子、腰椎活动度及不良反应。结果对照组总有效率75%,研究组治疗总有效率92%,2组差异有统计学意义(P<0.05)。相比于对照组,研究组治疗后VAS及ODI评分、白细胞介素-6(IL-6)及肿瘤坏死因子-α(TNF-α)水平均较低,JOA评分较高,2组差异有统计学意义(P<0.05)。治疗后相比于对照组,研究组腰椎活动度均较大,差异有统计学意义(P<0.05)。2组治疗期间均未出现不良反应。结论慢性腰肌劳损患者应用臭氧联合利多卡因痛点注射治疗效果显著,有助于减轻腰部疼痛感,改善腰椎功能,抑制炎性因子水平,提升腰椎活动度,减轻腰部功能障碍,无明显不良反应,安全可靠,值得推广应用。Objective To explore the clinical effect of ozone combined with lidocaine pain point injection in patients with chronic lumbar muscle strain.Methods According to the random number table,a total of 80 pa-tients with chronic lumbar muscle strain admitted to Zhengzhou Bone Injury Hospital of Traditional Chinese Medicine from July 2021 to August 2023 were divided into a study group(40 cases)and a control group(40 cas-es).The control group was treated with lidocaine pain point injection,while the study group received ozone therapy in addition to the same treatment as the control group.Both groups were treated for 1 course of treatment.The clinical efficacy,pain scale(VAS),lumbar function(JOA),lumbar dysfunction index(ODI),inflammatory factors,lumbar motion and adverse reactions were compared between the two groups.Results The total effective rate of the treatment in the research group was significantly higher than that in the control group(92%vs 75%),and the difference was statistically significant(P<0.05).Compared with the control group,the VAS and ODI scores,inter-leukin-6(IL-6)and tumor necrosis factor-α(TNF-α)levels in the study group were lower after treatment,but the JOA score was higher,and the difference was statistically significant(P<0.05).Compared with the control group,the study group showed significantly higher waist mobility in all directions after treatment(P<0.05).There were no adverse reactions during treatment in both groups.Conclusion The treatment effect of ozone combined with lido-caine pain point injection in patients with chronic lumbar muscle strain is significant,which can help to alleviate lumbar pain,improve lumbar function,inhibit the level of inflammatory factors,enhance lumbar motion,and re-duce lumbar dysfunction,without obvious adverse reactions,and is safe and reliable,worthy of promotion and ap-plication.

关 键 词：慢性腰肌劳损 臭氧 利多卡因 痛点注射 炎性因子 

分 类 号：R681.5[医药卫生—骨科学]