A major pain in the hip-Destruction of the left acetabulum and femoral head secondary to Tuberculosis:A case report and review of the literature  

作　　者：Dominic A.Haigh Dillan Mistry Hamzah Z.Farooq Katherine M.B.Ajdukiewicz 

机构地区：[1]Department of Infectious Diseases and Tropical Medicine,North Manchester General Hospital,M85RB Manchester,UK [2]Department of Virology,Manchester University NHS Foundation Trust,M139WL Manchester,UK [3]Faculty of Biology,Medicine and Health,University of Manchester,M139PL Manchester,UK

出　　处：《Infectious Medicine》2024年第1期71-74,共4页感染医学（英文）

摘　　要：A 68-year-old-gentleman presented with left hip pain,night sweats,fatigue,and weight loss.He had previously experienced pain with white discharge until he underwent an arthroscopic washout and reduction.The left lower limb was shortened and wasted with limited hip movements.He had recently travelled to Zambia,his country of origin.Imaging demonstrated a large mass with chronic erosions of the acetabulum and femoral head.Syn-ovial biopsy grew Mycobacterium tuberculosis,which was treated with rifampicin,isoniazid,pyrazinamide,and ethambutol for 2 months then 4 months of rifampicin and isoniazid.Whole genome sequencing indicated full sensitivity.Complex reconstructive surgery is scheduled,with a custom femoral head and acetabulum.This case illustrates the importance of considering tuberculosis in patients with erosive joint pathology and a multidisci-plinary approach as delayed diagnosis results in high morbidity.Prompt diagnosis using newer modalities such as whole genome sequencing on synovial fluid can enable timely treatment.

关 键 词：TUBERCULOSIS Tuberculous arthritis Mycobacterium tuberculosis 

分 类 号：R521[医药卫生—内科学]