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作 者:Wenhui Wang Xiyue Zhang Anke Zhang Han Yu Xinbao Kang Cheng Wang Yang Song Jiahua Ni Mikhail L.Zheludkevich Xiaonong Zhang
机构地区:[1]State Key Laboratory of Metal Matrix Composites,School of Materials Science and Engineering,Shanghai Jiao Tong University,Shanghai,China [2]College of Biological Science and Medical Engineering,Donghua University,Shanghai,China [3]The Second Affiliated Hospital,Zhejiang University,Zhejiang,China [4]Institute of Surface Science,Helmholtz-Zentrum Hereon,Geesthacht,21502,Germany [5]Suzhou Origin Medical Technology Co.Ltd.,Jiangsu,China
出 处:《Bioactive Materials》2024年第11期371-384,共14页生物活性材料(英文)
基 金:National Natural Science Foundation of China(No.52201300);National Key R&D Program of China(No.2023YFC2416800);Fundamental Research Funds for the Central Universities(2232024D-34);China Postdoctoral Science Foundation(No.2021M702090);Changshu Science and Technology Program(Industrial)Project(No.CG202107).
摘 要:Improving the comprehensive performance of low alloyed Mg is a significant challenge for biomedical applications.This paper developed a high-performance Mg–Zn alloy with uniform ultrafine grains and nano-precipitates through a straightforward,high-temperature reciprocating equal channel angle extrusion(ECAP)process and researched the microstructure,mechanical property,degradation behaviour,and biocompatibility of the developed alloy.Results showed that the lean Mg–2Zn alloy successfully refined grain to about 1μm and produced plenty of nano-particles with uniform distribution,providing high comprehensive mechanical properties(YS:235 MPa,UTS:267 MPa,EL:15.6%).Additionally,Zn-riched nano-particles in the matrix could decrease the Zn aggregation at the corrosion layer-matrix interface and form a dense oxide film,achieving a low degradation rate(0.13 mm/year in vivo).Finally,this work realizes the low alloy content,low cost,and good properties of one biodegradable Mg alloy,which will benefit the promotion of future clinical applications.
关 键 词:Biodegradable metal Mg alloy Ultrafine grains NANOPARTICLES ECAP
分 类 号:TG146.22[一般工业技术—材料科学与工程]
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