Recent advances in(4+3)cycloaddition of allenes  

作　　者：Yanyan Que Wenli Lei Yin Fang Shuzhong He Yang Chen 

机构地区：[1]School of Pharmaceutical Sciences,Guizhou Engineering Laboratory for Synthetic Drugs,Guizhou University,Guiyan 550025,China [2]State Key Laboratory of Natural and Biomimetic Drugs,Peking University,Beijing 100191,China

出　　处：《Green Synthesis and Catalysis》2024年第4期270-276,共7页绿色合成与催化（英文）

基　　金：financial support from the supported by National Natural Science Foundation of China(Nos.22061008 and 22361008);the State Key Laboratory of Natural and Biomimetic Drugs(No.K202223);the Science and Technology Foundation of Guizhou Province(Nos.ZK[2021]-039 and[2023]-097);the State Key Laboratory of Functions and Applications of Medicinal Plants,Guizhou Medical University(No.FAMP202102K).

摘　　要：Allenes are a class of unsaturated compounds containing a propadiene structural moiety,exhibiting essential physiological,pharmacological,and various reactivities.Their(4+3)cycloaddition reaction has become an effective method for synthesizing seven-membered rings,especially for heterocycles.This method has been continuously improved and developed.Herein,we review the(4+3)cycloaddition of allenes,focusing on the developed methodologies and the outlook in this field from 2013 to 2023.

关 键 词：ALLENES (4+3)Cycloaddition Asymmetric catalysis Seven-membered heterocycles 

分 类 号：O62[理学—有机化学]