左心房容积及应变参数与急性前壁心肌梗死预后的关系  

Relationship Between Left Atrial Volume and Strain Parameters and Prognosis of Acute Anterior Myocardial Infarction

作　　者：李馨 蒲鹏 LI Xin;PU Peng(Department of Cardiovascular,Chongqing Red Cross Hospital(Jiangbei District People's Hospital),Chongqing 400020,China)

机构地区：[1]重庆市红十字会医院(江北区人民医院)心血管内科,重庆400020

出　　处：《转化医学杂志》2024年第3期434-436,共3页Translational Medicine Journal

基　　金：重庆市科卫联合医学科研项目(2023MSXM032)。

摘　　要：目的 分析左心房容积及应变参数与急性前壁心肌梗死(AAMI)预后的关系。方法 选取2022年1月至2023年12月于重庆市红十字会医院行经皮冠状动脉介入(PCI)术的105例AAMI患者纳入研究,收集其临床资料并检测其左心房容积[左心房最大容积(LAVmax)、左心房最小容积(LAVmin)、左心房收缩前容积(LAVpre)]及应变参数[左心房存储应变(LASr)、左心房通道应变(LAScd)、左心房收缩应变(LASct)],随访3个月,以主要不良心血管事件(MACE)发生情况将其分为良好组与不良组,多因素Logistic回归分析MACE发生影响因素。结果 37例患者发生MACE,发生率为35.24%;不良组> 65岁和高血压史占比、LAVmin、LAVmax及LAVpre水平明显更高,LASr、LAScd及LASct水平明显更低(均P <0.05);> 65岁、高血压史、左心房容积增大及左心房应变参数水平较低是MACE发生的独立危险因素(P <0.05)。结论 左心房容积增大、左心房应变参数水平较低可增高AAMI患者术后MACE发生风险,与其预后具有相关性。Objective To analyze the relationship between left atrial volume,deformation parameters and prognosis in patients with acute anterior myocardial infarction(AAMI).Methods 105 AAMI patients who underwent PCI at our hospital from 2022 to 2023 were included.Their clinical data,including left atrial volume(LAVmax,LAVmin,LAVpre)and deformation parameters(LASr,LAScd,LASct),were collected.A three-month follow-up was conducted.The patients were divided into the good prognosis group and the poor prognosis group according to the occurrence of major adverse cardiovascular events(MACE).The factors affecting MACE were investigated by multivariate logistic regression analysis.Results In this study,37 patients had MACE,with an incidence rate of 35.24%.The proportion of patients with age>65 years,hypertension history,and the levels of LAVmin,LAVmax,and LAVpre were significantly higher in the poor prognosis group,while the levels of LASr,LAScd,and LASct were significantly lower(P<0.05).Age>65 years,hypertension history,enlarged left atrial volume,and lower levels of left atrial deformation parameters were independent risk factors for postoperative MACE in AAMI patients(P<0.05).Conclusion Enlar ged left atrial volume and lower levels of left atrial deformation parameters could increase the risk of postoperative MACE in AAMI patients and were related to their prognosis.

关 键 词：急性前壁心肌梗死 左心房容积 左心房应变参数 预后 LOGISTIC模型 

分 类 号：R542.22[医药卫生—心血管疾病] R814.43[医药卫生—内科学]