Keratinous and corneous-based products towards circular bioeconomy: A research review  

作　　者：Giovanni Davide Barone Irene Tagliaro Rodrigo Oliver-Simancas Matteo Radice Livia M.Kalossaka Michele Mattei Antonino Biundo Isabella Pisano Amparo Jiménez-Quero 

机构地区：[1]Institute of Biology,University of Graz,8010,Graz,Austria [2]Department of Materials Science,University of Milano-Bicocca,20126,Milano,Italy [3]Division of Industrial Biotechnology,Department of Life Sciences,Chalmers University of Technology,Gothenburg,41296,Sweden [4]Department of Biosciences,Biotechnology and Biopharmaceutics,University of Bari Aldo Moro,Via E.Orabona,4,70125,Bari,Italy [5]Department of Chemistry,Molecular Sciences Research Hub,Imperial College London,W120BZ London,United Kingdom [6]Libera UniversitàInternazionale Degli Studi Sociali“Guido Carli”,I-00198,Rome,Italy [7]CIRCC-Interuniversity Consortium Chemical Reactivity and Catalysis,Via C.Ulpiani 27,70126,Bari,Italy

出　　处：《Environmental Science and Ecotechnology》2024年第6期25-37,共13页环境科学与生态技术（英文）

基　　金：European Union's Horizon Europe research and innovation programme under grant agreement No.101060607;for the research and innovation programme under grant agreement No.101037796;National Recovery and Resilience Plan(NRRP),Mission 4.Component 2 Investment 1.3-Call for proposals No.341 of March 15,2022 of Italian Ministry of University and Research funded by the European Union-NextGenerationEU;Award Number:Project code PE00000003,Concession Decree No.1550 of October 11,2022 adopted by the Italian Ministry of University and Research,CUP H93C22000630001,Project title“ON Foods-Research and innovation network on food and nutrition Sustainability,Safety and Security-Working ON Foods”.

摘　　要：Keratins and corneous proteins are key components of biomaterials used in a wide range of applications and are potential substitutes for petrochemical-based products. Horns, hooves, feathers, claws, and similar animal tissues are abundant sources of α-keratin and corneous β-proteins, which are by-products of the food industry. Their close association with the meat industry raises environmental and ethical concerns regarding their disposal. To promote an eco-friendly and circular use of these materials in novel applications, efforts have focused on recovering these residues to develop sustainable, non-animal-related, affordable, and scalable procedures. Here, we review and examine biotechnological methods for extracting and expressing α-keratins and corneous β-proteins in microorganisms. This review highlights consolidated research trends in biomaterials, medical devices, food supplements, and packaging, demonstrating the keratin industry's potential to create innovative value-added products. Additionally, it analyzes the state of the art of related intellectual property and market size to underscore the potential within a circular bioeconomic model.

关 键 词：Alpha-keratin Corneous beta-protein Environmentally sustainable technology BIOTECHNOLOGY Resource recovery 

分 类 号：X321[环境科学与工程—环境工程]