我国消除HBV母婴传播的实施案例与经验介绍  

Experience in eliminating the mother-to-child transmission of hepatitis B virus in China

作　　者：罗雅丽[1] 王维[1] 潘禹辰[2] 姜晶[2] 郑寒龙[3] 吴雪丽[3] 陈慧[4] 朱世奔 侯金林[5] LUO Yali;WANG Wei;PAN Yuchen;JIANG Jing;ZHENG Hanlong;WU Xueli;CHEN Hui;ZHU Shiben;HOU Jinlin(Department of Healthcare,Maternal and Child Health Hospital of Bao’an District,Shenzhen,Guangdong 518100,China;Clinical Epidemiology Laboratory,The First Hospital of Jilin University,Changchun 130021,China;Department of Healthcare,Foshan Maternal and Child Health Hospital,Foshan,Guangdong 528000,China;Department of Hepatology,Hepatobiliary Hospital of Jilin,Changchun 130062,China;Department of Infectious Diseases and Hepatology Unit,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China)

机构地区：[1]深圳市宝安区妇幼保健院保健部,广东深圳518100 [2]吉林大学第一医院临床流行病学研究室,长春130021 [3]佛山市妇幼保健院保健部,广东佛山528000 [4]吉林省肝胆病医院肝病内科,长春130062 [5]南方医科大学南方医院感染内科暨肝病中心,广州510515

出　　处：《临床肝胆病杂志》2024年第11期2145-2151,共7页Journal of Clinical Hepatology

基　　金：国家重点研发计划(2022YFC2303600)。

摘　　要：HBV母婴传播的减少是实现消除HBV的关键步骤。“乙肝母婴零传播工程”(“小贝壳”项目)于2015年7月在北京人民大会堂正式启动,是集科学防治和应用性研究于一体的公益项目,目的是通过移动医疗工具“小贝壳”手机应用软件对乙型肝炎孕妇进行规范化管理,以进一步减少甚至消除HBV母婴传播。目前,“小贝壳”项目已覆盖全国,为阻断HBV母婴传播提供了详细的实施策略、成功的实践经验及可靠的数据支持,对全球实现消除HBV母婴传播具有重要价值。本文详细介绍了4个典型案例的“小贝壳”项目实施策略及其成效,为进一步理解和阻断母婴传播提供了有力证据。Reducing the mother-to-child transmission of hepatitis B virus(HBV)is crucial for achieving HBV elimination.Launched in July 2015 at the Great Hall of the People in Beijing,China,the“Zero Hepatitis B Mother-to-Child Transmission Project”(Shield Project)is a public welfare initiative integrating scientific prevention and applied research and aims to perform standardized management of pregnant women with hepatitis B using the mobile application of“Shield Project”,in order to further reduce or eliminate the mother-to-child transmission of HBV.At present,the Shield Project has expanded nationwide,offering detailed implementation strategies,successful practices,and reliable data to support the global effort to eliminate the mother-tochild transmission of HBV.This article introduces the implementation strategies and outcomes of the Shield Project in four representative cases,in order to provide strong evidence for further understanding and preventing the mother-to-child transmission of HBV.

关 键 词：乙型肝炎病毒 传染性疾病传播 垂直 “小贝壳”项目 

分 类 号：R714.251[医药卫生—妇产科学]