间歇蓝光照射对新生儿高胆红素血症患儿胆红素的影响  

Effect of Intermittent Blue Light Irradiation on Bilirubin for Neonatal Hyperbilirubinemia

作　　者：朱晓花 ZHU Xiaohua(Department of Pediatrics,Anfu County Maternal and Child Health Hospital,Anfu 343200,Jiangxi,China)

机构地区：[1]安福县妇幼保健院儿科,江西安福343200

出　　处：《医学信息》2024年第22期66-69,共4页Journal of Medical Information

摘　　要：目的研究间歇蓝光照射对新生儿高胆红素血症(NHB)患儿胆红素指标的影响。方法选取2019年1月-2022年12月安福县妇幼保健院儿科收治的72例NHB患儿,经随机数字表法分为对照组(36例)与观察组(36例),对照组采用持续蓝光照射治疗,观察组采用间歇蓝光照射治疗,比较两组临床疗效、黄疸指数、血清总胆红素(TBIL)水平、不适反应、黄疸消退时间、哭闹时长、睡眠时长。结果两组治疗总有效率比较,差异无统计学意义(P>0.05);两组治疗后黄疸指数、TBIL水平均低于治疗前(P<0.05),但组间比较,差异无统计学意义(P>0.05);观察组不适反应发生率为5.56%,低于对照组的19.44%(P<0.05)。两组黄疸消退时间比较,差异无统计学意义(P>0.05),但观察组哭闹时长短于对照组,睡眠时长长于对照组(P<0.05)。结论间歇蓝光照射治疗NHB效果确切,其疗效与持续蓝光照射方案相当,可降低患儿TBIL浓度,消退黄疸的同时,减少其不适反应与哭闹时长,改善患儿睡眠质量。Objective To study the effect of intermittent blue light irradiation on bilirubin indexes in neonatal hyperbilirubinemia(NHB).Methods A total of 72 children with NHB admitted to the Department of Pediatrics of Anfu County Maternal and Child Health Hospital from January 2019 to December 2022 were selected and divided into control group(36 children)and observation group(36 children)by random number table method.The control group was treated with continuous blue light irradiation,and the observation group was treated with intermittent blue light irradiation.The clinical efficacy,jaundice index,serum total bilirubin(TBIL)level,discomfort reaction,jaundice regression time,crying time and sleep time were compared between the two groups.Results There was no significant difference in the total effective rate between the two groups(P>0.05).The jaundice index and TBIL level of the two groups after treatment were lower than those before treatment(P<0.05),while there was no significant difference between the two groups(P>0.05).The incidence of discomfort in the observation group was 5.56%,which was lower than 19.44%in the control group(P<0.05).There was no significant difference in jaundice regression time between the two groups(P>0.05),but the crying time of the observation group was longer than that of the control group,and the sleep time was longer than that of the control group(P<0.05).Conclusion Intermittent blue light irradiation is effective in the treatment of NHB,and its efficacy is comparable to that of continuous blue light irradiation.Meanwhile,it can reduce the concentration of TBIL in children,eliminate jaundice,reduce the duration of discomfort and crying,and improve the sleep quality of children.

关 键 词：新生儿高胆红素血症 间歇蓝光照射 黄疸指数 胆红素 持续蓝光照射 睡眠质量 

分 类 号：R722.17[医药卫生—儿科]