胎膜早破、羊水混浊剖宫产产妇羊水与胎膜细菌培养及药敏结果分析  

Analysis of Bacterial Culture and Drug Sensitivity Results of Amniotic Fluid and Fetal Membrane in Cesarean Section Women with Premature Rupture of Membranes and Amniotic Fluid Turbidity

作　　者：何梗秀 唐晓燕 幸珺娟 HE Gengxiu;TANG Xiaoyan;XING Junjuan(Hospital-Acquired Infection Control Department,Yudu County Maternal and Child Health Hospital,Yudu 342300,Jiangxi,China)

机构地区：[1]于都县妇幼保健院院感科,江西于都342300

出　　处：《医学信息》2024年第22期98-101,共4页Journal of Medical Information

基　　金：赣州市指导性科技计划项目(编号:GZ2023ZSF760)。

摘　　要：目的分析胎膜早破、羊水混浊剖宫产产妇羊水与胎膜的细菌培养及药敏结果。方法选取于都妇幼保健院2022年1月-2023年12月采集的102例羊水与胎膜标本(胎膜早破54例、羊水混浊48例),进行细菌培养及药敏试验,统计羊水与胎膜标本的病原菌检出率,分析主要病原菌对不同抗菌药物的耐药性情况。结果102例样本中,革兰氏阴性菌共检出67株,检出率为65.69%,其主要致病菌为大肠埃希菌,占总样本51.96%(53/102);革兰氏阳性菌共检出35株,检出率为34.31%,其主要致病菌为粪肠球菌,占总样本20.59%(21/102)。药敏结果显示,大肠埃希菌对氨苄西林的耐药率最高86.79%,其次为头孢唑啉67.92%,对其他抗生素均较为敏感,其敏感率均大于65%。同时,粪肠球菌对氨苄西林、青霉素的敏感率最高,达95.24%,对其他抗生素较为耐药,耐药率均高于50%。结论革兰氏阴性菌与革兰氏阳性菌为胎膜早破常见致病菌,前者占比较多,其主要病原菌为大肠埃希菌,对氨苄西林、头孢唑啉具有较高耐药性,对其他药物则较为敏感;后者主要病原菌为粪肠球菌,对氨苄西林、青霉素最为敏感,在其他药物中则具有较高耐药性。Objective To analyze the results of bacterial culture and drug sensitivity of amniotic fluid and fetal membranes in cesarean section women with premature rupture of membranes and amniotic fluid turbidity.Methods A total of 102 amniotic fluid and fetal membrane specimens(54 cases of premature rupture of membranes and 48 cases of amniotic fluid turbidity)collected from January 2022 to December 2023 in Yudu Maternal and Child Health Hospital were selected for bacterial culture and drug sensitivity test.The detection rate of pathogenic bacteria in amniotic fluid and fetal membrane specimens was counted,and the drug resistance of main pathogenic bacteria to different antibiotics was analyzed.Results Among the 102 samples,67 strains of Gram-negative bacteria were detected,with a detection rate of 65.69%.The main pathogenic bacteria were Escherichia coli,accounting for 51.96%(53/102)of the total samples.A total of 35 strains of Gram-positive bacteria were detected,with a detection rate of 34.31%.The main pathogenic bacteria were Enterococcus faecalis,accounting for 20.59%(21/102)of the total sample.The results of drug sensitivity showed that the resistance rate of Escherichia coli to ampicillin was the highest(86.79%),followed by cefazolin(67.92%).Escherichia coli was sensitive to other antibiotics,and the sensitivity rate was more than 65%.At the same time,the sensitivity of Enterococcus faecalis to ampicillin and penicillin was the highest,reaching 95.24%,and it was more resistant to other antibiotics,and the resistance rate was higher than 50%.Conclusion Gram-negative bacteria and Gram-positive bacteria are common pathogens of premature rupture of membranes.The former accounts for a large proportion.The main pathogen is Escherichia coli,which has high resistance to ampicillin and cefazolin,and is sensitive to other drugs.The main pathogen of the latter is Enterococcus faecalis,which is most sensitive to ampicillin and penicillin,and has high drug resistance in other drugs.

关 键 词：胎膜早破 羊水混浊 剖宫产 羊水与胎膜标本 细菌培养 药敏试验 

分 类 号：R714.4[医药卫生—妇产科学]