一种新型水杨醛席夫碱荧光探针的合成及性能研究  

Synthesis and Property of A Novel Salicylaldehyde Schiff Base Fluorescent Probe

作　　者：惠朴真 吴静 吴昊 周立超 王慧 吕帆 谷晓霞 HUI Puzhen;WU Jing;WU Hao;ZHOU Lichao;WANG Hui;LYU Fan;GU Xiaoxia(School of Pharmacy,Wannan Medical College,Wuhu 241002,China)

机构地区：[1]皖南医学院药学院,安徽芜湖241002

出　　处：《杭州师范大学学报（自然科学版）》2024年第6期620-626,共7页Journal of Hangzhou Normal University(Natural Science Edition)

基　　金：国家级大学生创新创业训练计划项目(202310368050).

摘　　要：通过色胺和4-(二乙氨基)水杨醛的缩合反应,成功制备了一种新型席夫碱荧光探针4-(二乙氨基)水杨醛缩色胺席夫碱(探针L),并采用核磁共振和元素分析等物理化学手段对其结构进行了表征.结果表明:探针L对Zn^(2+)具有很高的选择性,Zn^(2+)的检测阈值可以达到29.1 nmol·L-1;Job曲线揭示探针L与Zn^(2+)以2∶1的物质的量之比配位,经结构解析进一步确认了L与Zn^(2+)的配位形式.A novel fluorescent probe 4-(diethylamino)salicylaldehyde tryptamine Schiff base(probe L)was generated by the condensation reaction of tryptamine and 4-(diethylamino)salicylaldehyde,and its structure was characterized by nuclear magnetic resonance and elemental analysis.The results showed that probe L was highly selective to Zn^(2+),and the detection threshold of Zn^(2+)could reach 29.1 nmol·L-1.The Job curve revealed the coordination of probe L and Zn^(2+)in the amount of matter of 2∶1,and the structure analysis further confirms the coordination form of L and Zn^(2+).

关 键 词：4-(二乙氨基)水杨醛缩色胺席夫碱 荧光探针 Zn^(2+) 

分 类 号：O625.6[理学—有机化学]