鼻内镜手术患者麻醉诱导前应用利多卡因胶浆的效果观察  

Effect of Lidocaine Glue before Induction of Anesthesia in Patients undergoing Nasal Endoscopic Surgery

作　　者：王阿艳 赫琳珺 Wang Ayan;He Linjun(Department of Surgery and Anesthesiology,Xi'an Metallurgical Hospital1,Xi'an 710000,Shaanxi Province,China;Department of Surgery and Anesthesiology,Hancheng Mining Bureau General Hospital2,Hancheng 715400,Shaanxi Province,China)

机构地区：[1]西安冶金医院手术麻醉科,陕西西安710000 [2]韩城矿务局总医院手术麻醉科,陕西韩城715400

出　　处：《中外医药研究》2024年第30期70-72,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:观察鼻内镜手术患者麻醉诱导前应用利多卡因胶浆的效果。方法:选取2022年11月—2024年3月于西安冶金医院行鼻内镜手术患者83例纳入研究,以随机数表法将患者分为对照组(n=41)和观察组(n=42),观察组在麻醉诱导前口服2%利多卡因胶浆1 mg/kg,对照组则给予同等剂量生理盐水。比较两组麻醉前(T_(0))、插管即刻(T_(1))、手术开始后5 min(T_(2))、手术开始后30 min(T_(3))、手术结束时(T_(4))时血流动力学[心率(HR)、平均动脉压(MAP)、血氧饱和度(SpO_(2))],T_(2)、T_(3)的术野质量,苏醒期指标与术后不良反应发生情况。结果:T_(1)、T_(2)及T_(3),观察组HR、MAP及SpO_(2)水平均低于对照组(P<0.05)。T_(2)及T_(3),观察组Fromme术野评分低于对照组(P<0.05)。观察组自主呼吸恢复时间、语言指令反应时间及麻醉复苏室停留时间均短于对照组(P<0.05)。两组术后不良反应总发生率比较,差异无统计学意义(P>0.05)。结论:鼻内镜手术患者麻醉诱导前应用利多卡因胶浆可有效维持围术期血流动力学稳定,改善术野质量与苏醒质量,且安全性较高。Objective:To observe the effect of lidocaine glue before anesthesia induction in patients undergoing nasal endoscopic surgery.Methods:A total of eighty-thee patients who underwent nasal endoscopic surgery in Xi'an Metallurgical Hospital from November 2022 to March 2024 were selected for the study.The patients were divided into control group(n=41)and observation group(n=42)by random number table method.The observation group was given 2%lidocaine glue 1 mg/kg orally before induction of anesthesia,while the control group was given the same dose of normal saline.The hemodynamic parameters[heart rate(HR),mean arterial pressure(MAP),and blood oxygen saturation(SpO_(2))]before anesthesia(T_(0)),immediately after intubation(T_(1)),5 minutes after the start of surgery(T_(2)),30 minutes after the start of surgery(T_(3)),and at the end of surgery(T_(4))between two groups,as well as the quality of the surgical field,recovery indicators,and incidence of postoperative adverse reactions at T_(2) and T_(3) were compared.Results:The levels of HR,MAP and SpO_(2)in T_(1),T_(2) and T_(3) in observation group were lower than those in control group(P<0.05);T_(2) and T_(3),Fromme scores in observation group were lower than those in control group(P<0.05);the recovery time of spontaneous respiration,the response time of verbal instruction and the stay time of anesthesia resuscitation room in the observation group were shorter than those in the control group(P<0.05);there was no significant difference in the total incidence of postoperative adverse reactions between the two groups(P>0.05).Conclusion:The application of lidocaine glue before anesthesia induction in patients undergoing nasal endoscopic surgery can effectively maintain the stability of perioperative hemodynamics,improve the quality of the operating field and the quality of recovery,with high safety.

关 键 词：鼻内镜 麻醉诱导 利多卡因胶浆 Fromme术野评分 苏醒质量 

分 类 号：R765.9[医药卫生—耳鼻咽喉科]