Skin photobiological effect induced by BL:Clinical manifestation,mechanisms,and protection against photodamages  

作　　者：Tao Zhang Malyn Ungsurungsie Liu Yue Junxiang Li Baoxia Zhuang Wenyu Ding Xuhui Li 

机构地区：[1]Research and Development Center,Better Way(Shanghai)Cosmetics Co.Ltd.,Shanghai 201400,China [2]Research,Development and Innovation Division,S&J International Enterprises PCL,Bankok 10120,Thailand [3]AGECODE R&D CENTER,Yangtze Delta Region Institute of Tsinghua University Zhejiang,Jiaxing 314000,China [4]Harvest Biotech(Zhejiang)Co.,Ltd.,Jiaxing 314000,China [5]Zhejiang Provincial Key Laboratory of Applied Enzymology,Yangtze Delta Region Institute of Tsinghua University,Jiaxing 314000,China

出　　处：《Journal of Dermatologic Science and Cosmetic Technology》2024年第3期72-78,共7页皮肤科学与化妆品技术期刊（英文）

摘　　要：Over the last decade,the rapid advances of life sciences have significantly increased public awareness and comprehension of dermatological knowledge,resulting in widespread acceptance of scientific skincare in society.The scope of photoprotection has expanded to encompass not only ultraviolet radiation but also visible light(including blue light).Furthermore,photoprotection methods have evolved from light blocking to the repair of cellular damage caused by prolonged light exposure via biological signaling pathways.Blue light(BL)is the portion of sunlight between 400 nm(violet)and 500 nm(cyan),that can penetrate deep into biological tissues,with up to 20%reaching subcutaneous tissues.Similar to UV damage,BL can cause oxidative stress,persistent pigmentation,and extracellular matrix degradation,resulting in skin symptoms such as hyperpigmentation,dullness,lack of radiance,uneven skin tone,and wrinkles.This study investigates the clinical manifestations of BL-induced skin photodamages,as well as the underlying biological mechanisms and proposes rational photoaging prevention strategies.

关 键 词：Blue light Skin pigmentation PHOTOAGING 

分 类 号：R751[医药卫生—皮肤病学与性病学]