Expert consensus on the technical specifications of the in vitro skin penetration test of cosmetic product by Franz diffusion cell  

作　　者：Bingwen Liang Liling Zhou Chuanbin Wu Liang Fang Lisheng Wang Lihua Peng Peng Shu Lifeng Tang Yu Bei Xiaodong Cui Xiaojia Chen Yuan Gao Chong Han Yan Jia Huaqing Lim Yifang Li Ying Liu Yiguang Li Zhiwei Li Zixiu Liu Shaohua Ren Jun Shi Wanyang Sun Lijuan Tian Qun Wang Yuan Wang Yuehong Xu Ming Zeng Quangang Zhu Shu Zhang Yifan Zhang Qi Xiang 

机构地区：[1]The transdermal Drug Delivery Committee of the World Federation of Chinese Medicine Societies,Beijing 100020,China [2]Guangzhou University of Chinese Medicine,Guangzhou 510006,China [3]Jinan University,Guangzhou 510632,China [4]Shenyang Pharmaceutical University,Shenyang 110016,China [5]Zhejiang University,Hangzhou 310058,China [6]Shenzhen Hujia Technology Co.,Ltd.,Shenzhen 518066,China [7]Guangzhou Xika Technology Co.,Ltd.,Guangzhou 510653,China [8]Guangzhou Kingtest Technology Co.,Ltd.,Guangzhou 510663,China [9]China Council for the Promotion of national Trade,Beijing 100020,China [10]Fudan University,Shanghai 200433,China [11]Guangdong Lewwin Pharmaceutical Research Institute Co.,Ltd.,Guangzhou 510900,China [12]Beijing Technology and Business University,Beijing 10048,China [13]Guangdong Pharmaceutical University,Guangzhou 510006,China [14]Heizhimei(Guangzhou)Biotechnology Co.,Ltd.,Guangzhou 510700,China [15]Jinan University Cosmetics and Medical Industry Alumni Association,Guangzhou 510000,China [16]Novozen Technology(Shanghai)Co.,Ltd.,Shanghai 200120,China [17]Sun Yat-Sen University,Zhuhai 510275,China [18]The Sixth Affiliated Hospital,Sun Yat-sen University Guangdong Gastrointestinal Hospital,Guangzhou 510655,China [19]Shanghai Skin Diseases Hospital,Shanghai 200443,China [20]Biopharmaceutical R&D Center of Jinan University,Guangzhou 510665,China

出　　处：《Journal of Dermatologic Science and Cosmetic Technology》2024年第3期79-85,共7页皮肤科学与化妆品技术期刊（英文）

摘　　要：Background:Diffusion cell test is one of the most commonly used in vitro model to detect the percutaneous absorption of cosmetic ingredients.Although PRC State Administration of Quality Supervision and Quarantine has issued the guideline for the in vitro test method for the percutaneous absorption of drug molecules,there is still a lack of guideline for the percutaneous absorption test of cosmetic components.Objective:In order to improve the standardized level and make the in vitro percutaneous absorption test of cosmetic ingredients more comparable,based on the international and domestic experience,Transdermal Drug Delivery Committee of the World Federation of Chinese Medicine Societies organized the experts to discuss and formed this consensus as reference for the percutaneous absorption test of cosmetic components.Materials and Methods:To standardize the in vitro diffusion cell test technique for transdermal penetration of functional cosmetic ingredients,the Transdermal Drug Delivery Professional Committee of the World Federation of Societies of Traditional Chinese Medicine has organized many discussions among experts.

关 键 词：COSMETICS Percutaneous absorption Diffusion cell Expert consensus 

分 类 号：TQ658[化学工程—精细化工]