蛋氨酸对反刍动物肝脏健康的影响及其机制  

Effects of Methionine on Liver Health of Ruminants and Its Mechanisms

作　　者：姜佳利 席敏杰 王博[1] 张瑞阳 JIANG Jiali;XI Minjie;WANG Bo;ZHANG Ruiyang(College of Veterinary and Animal Science,Shenyang Agricultural University,Shenyang 110866,China)

机构地区：[1]沈阳农业大学动物科学与医学学院,沈阳110866

出　　处：《动物营养学报》2024年第11期6853-6863,共11页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：国家自然科学基金项目(32002214);辽宁省教育厅基本科研项目(JYTQN2023305);沈阳农业大学引进人才科研启动项目(880416010)。

摘　　要：蛋氨酸是反刍动物的第一限制性氨基酸,具有调节糖和脂代谢、抗炎、抗氧化等多重生理作用。因瘤胃微生物的降解作用,生产中常采用过瘤胃蛋氨酸(RPM)的形式为反刍动物补充蛋氨酸。作为动物机体营养物质的代谢中枢和重要的免疫器官,肝脏健康与动物生产性能和健康密切相关。研究发现,蛋氨酸可通过对肝脏代谢及其功能进行调控,进而可维护反刍动物的肝脏健康。因此,本文对蛋氨酸的理化性质及营养作用、RPM类型及其吸收进行概述,并对蛋氨酸对反刍动物肝脏健康的影响与机制展开综述,旨在为RPM在反刍动物生产中的应用提供科学依据和理论参考。Methionine is the first limiting amino acid in ruminants,which has multiple physiological functions,such as glucose and lipid metabolism,anti-inflammatory and antioxidant.Due to the degradation of rumen microbiota,rumen protected methionine(RPM)is often used to supplement ruminants with methionine in production.As the metabolic center of nutrients and important immune organ in ruminants,liver health is closely related to animal performance and health.Recent studies have demonstrated that methionine has regulatory effects on liver metabolism and functions,thus maintaining the liver health of ruminants.Therefore,the present study mainly reviews the physicochemical properties and nutritional functions of methionine,the types of RPM and its absorption,the effects and mechanisms of methionine on the liver health of ruminants.The present study may provide scientific basis and theoretical reference for the application of RPM in ruminant production.

关 键 词：过瘤胃蛋氨酸 反刍动物 肝脏 蛋氨酸代谢 糖代谢 脂代谢 

分 类 号：S816[农业科学—饲料科学]