不同凝固浴对再生纤维素超滤膜结构和性能的影响  

Effect of different coagulation baths on the structure and performance ofregenerated cellulose ultrafiltration membranes

作　　者：陈铭 杨淑娟 张勇[1,2] CHEN Ming;YANG Shujuan;ZHANG Yong(Key Laboratory of Advanced Textile Materials and Manufacturing Technology,Ministry of Education,Zhejiang Sci-Tech University,Hangzhou 310018,China;Zhejiang Sci-Tech University Xiangshan Knitting Institute Co.,Ltd.,Ningbo 315700,China)

机构地区：[1]浙江理工大学先进纺织材料与制备技术教育部重点实验室,杭州310018 [2]浙江理工大学象山针织研究院有限公司,宁波315700

出　　处：《丝绸》2024年第12期79-87,共9页Journal of Silk

基　　金：浙江省重点研发计划项目(2021C03160);浙江理工大学科学基金项目(21202297-Y)。

摘　　要：本文利用新型的常温纤维素溶解体系ZnCl_(2)/AlCl_(3)直接从棉浆中制备再生纤维素超滤膜,探讨了不同凝固浴对再生纤维素超滤膜结构和性能的影响。研究发现,当采用有机溶剂作为凝固浴时,可以提升相分离过程中溶剂—非溶剂的交换速度。随着凝固浴中有机溶剂比例的增加,可以使得膜表面致密皮层厚度增加、膜表面孔径大小减小,并使得膜内部出现非对称指状孔结构。在乙醇中得到的再生纤维素超滤膜的截留分子量(MWCO)可以达到314.5 kDa,水通量可以达到628.57 LMH/bar,并且能够分离病毒标志物2000 kDa的蓝色葡聚糖和人体免疫球蛋白(IgG)。结果表明,可以通过控制凝固浴中有机溶剂的比例来获取不同结构的再生纤维素超滤膜,并进一步展示了该种再生纤维素超滤膜在生物制药应用中的潜力。The application of various ultrafiltration membranes in biopharmaceutical production presents promising opportunities,offering effective separation of target substances with low energy consumption and minimal chemical additives.These membranes achieve effective separation of target substances from solutions while requiring minimal supplementary chemical additives.Materials such as polyethersulfone(PES),polyvinylidene difluoride(PVDF),and cellulose are commonly used for membrane fabrication.Among them,regenerated cellulose(RC)ultrafiltration membranes demonstrate unique advantages in practical filtration.Due to their excellent hydrophilicity of cellulose,they significantly reduce protein adsorption during filtration,thus prolonging membrane lifespan.Additionally,cellulose,being abundant and renewable,aligns with sustainability goals by mitigating environmental impact.The use of cellulose products can reduce the environmental impact of synthetic products,aligning with sustainability goals.However,the abundant hydrogen bonds and high crystallinity of cellulose make it nearly insoluble in common solvents,posing challenges for direct processing.Currently,most cellulose ultrafiltration membranes on the market are either cellulose acetate membranes or are obtained through hydrolyzing cellulose acetate membranes.Although chemical modification can enhance the processability of cellulose,the industrial production of cellulose derivatives still relies on heterogeneous reaction methods,which are typically limited to the surface of cellulose and difficult to control,leading to issues such as adverse reactions and waste.Developing efficient cellulose dissolution systems is necessary for directly dissolving and preparing RC products from cotton pulp.To meet the requirements of sustainable development,a series of low-cost and recyclable room-temperature cellulose solvents have been developed,enabling the clean preparation of green RC ultrafiltration membranes.To achieve the direct preparation of RC ultrafiltration membranes from

关 键 词：再生纤维素超滤膜 ZnCl_(2)/AlCl_(3) 相分离 有机溶剂 凝固浴 膜孔结构 分离性能 

分 类 号：TS102.51[轻工技术与工程—纺织工程]