严肃游戏对老年认知功能障碍病人记忆改善效果的Meta分析  

Effect of serious games on memory improvement in elderly patients with cognitive dysfunction:a Meta-analysis

作　　者：张雅芝 厉春林[1] ZHANG Yazhi;LI Chunlin(Tongji Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Hubei 430030 China)

机构地区：[1]华中科技大学同济医学院附属同济医院,湖北430030

出　　处：《循证护理》2024年第23期4192-4202,共11页Chinese Evidence-Based Nursing

基　　金：同济医院科研基金护理专项课题,编号:2023D44。

摘　　要：目的:通过Meta分析探索严肃游戏对老年认知功能障碍病人记忆改善效果。方法:计算机检索PubMed、EMbase、MedLine、the Cochrane Library、中国生物医学文献服务系统、中国知网、万方数据库等有关严肃游戏对老年认知功能障碍病人记忆改善效果的相关研究,检索时限为建库至2024年3月。由2名评价人员按照标准独立筛选文献、提取资料、评价文献质量。采用RevMan 5.3软件对资料进行Meta分析,采用推荐分级的评价、制订与评估(GRADE)系统对证据进行质量评级。结果:共纳入20篇文献,样本量为1 439例。Meta分析结果显示,严肃游戏能改善老年认知障碍病人的言语记忆[SMD=0.42,95%CI(0.19,0.66),Z=3.51,P=0.000 5]、空间记忆[SMD=0.32,95%CI(0.15,0.50),Z=3.68,P=0.000 2]、工作记忆[SMD=0.32,95%CI(0.13,0.51),Z=3.36,P=0.000 8]、短时记忆[SMD=0.47,95%CI(0.25,0.70),Z=4.09,P<0.000 1]和延迟回忆[SMD=0.62,95%CI(0.43,0.80),Z=6.44,P<0.000 01]。结论:现有证据表明,严肃游戏干预能改善老年认知障碍病人记忆功能,包括言语记忆、空间记忆、工作记忆、短时记忆、延迟回忆。临床护理工作人员可参照本研究结果,积极开展严肃游戏干预,改善临床老年认知障碍病人记忆功能。Objective:To explore the memory improvement effect of serious games on elderly patients with cognitive dysfunction by Meta-analysis.Methods:Related studies on the memory improvement effect of serious games on elderly patients with cognitive impairment were retrieved from PubMed,EMbase,MedLine,the Cochrane Library,SinoMed,CNKI,and WanFang Database.The retrieval time was from the inception to March 2024.Two reviewers screened the literature according to the inclusion and exclusion criteria,and extracted data,assessed the quality of included studies independently.Meta-analysis was conducted by RevMan 5.3 and GRADE were used for evidence quality rating.Results:A total of 20 studies were included,with a sample size of 1439 cases.Serious games could improved verbal memory(SMD=0.42,95%CI 0.19-0.66,Z=3.51,P=0.0005),spatial memory(SMD=0.32,95%CI 0.15-0.50,Z=3.68,P=0.0002),working memory(SMD=0.32,95%CI 0.13-0.51,Z=3.36,P=0.0008),short-term memory(SMD=0.47,95%CI 0.25-0.70,Z=4.09,P<0.0001)and delayed recall(SMD=0.62,95%CI 0.43-0.80,Z=6.44,P<0.00001)in elderly patients with cognitive impairment.Conclusion:Current evidence shows that serious games have the potential to improve verbal memory,spatial memory,working memory,short-term memory and delayed recall in older adults with cognitive impairment.Clinical nursing staff can refer to the results of this study,and actively carry out serious game intervention to improve the memory function of elderly patients with cognitive impairment.

关 键 词：严肃游戏 认知功能障碍 记忆功能 META分析 循证护理 

分 类 号：R473.74[医药卫生—护理学]