Advanced metal-organic frameworks-polymer platforms for accelerated dermal wound healing  

作　　者：Fereshte Hassanzadeh-Afruzi Mina Azizi Iman Zare Ehsan Nazarzadeh Zare Anwarul Hasan Siavash Iravani Pooyan Makvandi Yi Xu 

机构地区：[1]School of Chemistry,Damghan University,Damghan 36716-45667,Iran [2]Department of Nanobiotechnology/Biophysics,Faculty of Biological Science,Tarbiat Modares University,Tehran 14115-154,Iran [3]Research and Development Department,Sina Medical Biochemistry Technologies Co.,Ltd.,Shiraz 7178795844,Iran [4]Department of Mechanical and Industrial Engineering,Qatar University,Doha 2713,Qatar [5]Biomedical Research Center,Qatar University,Doha 2713,Qatar [6]Independent Researcher,W Nazar ST,Boostan Ave,Isfahan 81756-33551,Iran [7]Centre of Research Impact and Outcome,Chitkara University,Rajpura,Punjab 140401,India [8]Department of Biomaterials,Saveetha Dental College and Hospitals,SIMATS,Saveetha University,Chennai 600077,India [9]Department of Science&Technology,Department of Urology,NanoBioMed Group,The Quzhou Affiliated Hospital of Wenzhou Medical University,Quzhou People's Hospital,Quzhou 324000,China

出　　处：《Chinese Chemical Letters》2024年第11期57-65,共9页中国化学快报（英文版）

基　　金：A.Hasan acknowledges the partial financial support from the Grant(No.NPRP12S-0310-190276)。

摘　　要：Skin wound healing is an important aspect of regenerative medicine.Metal-organic frameworks(MOFs)have attracted considerable attention as promising nanomaterials for skin wound healing due to their remarkable versatility,tunable pore size,surface area,targeted delivery of various therapeutic agents,and controlled release properties.The combination of these materials with biocompatible and synthetic polymers can help improve their performance in wound regeneration.This review examines the potential of MOF-polymer composites in skin wound healing.Physical and biological chemical properties and methods of making MOFs and their composites have been investigated.In the final section of this review,challenges and future prospects for the development of MOF-polymer composites are stated.

关 键 词：Metal-organic frameworks Dermal wound healing Tissue engineering NANOCOMPOSITE Nanoparticles 

分 类 号：R318.08[医药卫生—生物医学工程] TB33[医药卫生—基础医学]