Photocatalyst/metal-free sequential C-N/C-S bond formation:Synthesis of S-arylisothioureas via photoinduced EDA complex activation  

作　　者：Guoju Guo Xufeng Li Jie Ma Yongjia Shi Jian Lv Daoshan Yang 

机构地区：[1]College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qingdao 266042,China [2]Zhejiang Wansheng Co.Ltd.,Linhai 317000,China [3]National Engineering Research Center of Low-Carbon Processing and Utilization of Forest Biomass,Nanjing Forestry University,Nanjing 210037,China

出　　处：《Chinese Chemical Letters》2024年第11期361-366,共6页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.22271170);the Scientific Research Foundation of Qingdao University of Science and Technology。

摘　　要：A photocatalyst-free visible-light-promoted three-component reaction of thianthrenium salts,isothiocyanates,and amines is presented,which affords a rapid and efficient approach to S-arylisothioureas under mild conditions.This developed method exhibits the advantages of readily available raw materials,broad substrate scope,good functional tolerance,and operational simplicity.It is worth mentioning that the byproduct thianthrene can be recycled in quantity,ultimately maximizing the atomic economy of the reaction and avoiding chemical waste.Mechanism investigations support the strategy involving a photoinduced EDA complex.

关 键 词：Visible-light Photocatalyst-free EDA complex Thianthrenium salts S-arylisothioureas 

分 类 号：O643.36[理学—物理化学] O644.1[理学—化学] O625.7