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机构地区:[1]TomoWave Laboratories,Inc,Houston,USA
出 处:《Photonics Insights》2024年第4期1-2,共2页光子学评论(英文)
摘 要:Thirty years ago,we demonstrated laser-based depth-resolved optoacoustic imaging of biological tissues^([1–3]),laying an important foundation for modern optoacoustic tomography(OAT)alternatively called photoacoustic computer tomography(PACT).Today,OAT/PACT has become one of the fastest-growing biomedical imaging technologies and has found a wide range of applications in biomedicine^([4,5]).Complementary to anatomical imaging of tissue structures with ultrasound,X-rays,and radiofrequency waves,OAT/PACT is a molecular imaging technology that employs diffused light absorbed by molecules in biological tissues and generates ultrasound signals resulting from thermal expansion of instantaneously heated tissue voxels.It uniquely visualizes endogenous tissue chromophores of hemoglobin and oxyhemoglobin,as well as nontoxic exogeneous chromophores of dyes and nanoparticles,and achieves imaging resolution of hundreds of microns at 3–5-cm depth in biological tissues^([6]).
关 键 词:uniquely PHOTOACOUSTIC HEATED
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