肠道线虫与肠道菌群相互作用的研究进展  

Research progress on the interaction between intestinal nematodes and intestinal flora

作　　者：张芷兰 尹思萱 吕芳丽 ZHANG Zhilan;YIN Sixuan;LV Fangli(Department of Parasitology,School of Medicine,Sun Yat-sen University,Shenzhen 518107,Guangdong,China;Scientific Research Center,the Seventh Affiliated Hospital of Sun Yat-sen University,Shenzhen 518107,Guangdong,China)

机构地区：[1]中山大学医学院寄生虫学教研室,广东深圳518107 [2]中山大学附属第七医院科研中心,广东深圳518107

出　　处：《中国寄生虫学与寄生虫病杂志》2024年第5期642-647,共6页Chinese Journal of Parasitology and Parasitic Diseases

基　　金：国家自然科学基金面上项目(82272366,81971955);深圳市自然科学基金面上项目(JCYJ20220530145002006);广东省自然科学基金面上项目(2021A1515012115,2019A1515011667);广东省研究生教育创新计划(2021SFKC003);中山大学校级本科教学质量工程项目(中大教务[2023] 96号、中大教务[2022] 91号)。

摘　　要：肠道菌群是人体肠道微环境的重要组成部分,在消化吸收、营养代谢、抵御病原体感染和调节自身免疫性疾病等方面起着重要作用。寄生于宿主肠道的寄生虫与宿主肠道菌群之间存在着复杂的相互作用,影响着宿主肠道的健康和相关疾病的发生发展。本文对宿主肠道线虫与肠道菌群相互作用的研究进展进行综述,以期为深入理解相关疾病的致病机制提供科学依据。The intestinal flora is an important component of human intestinal microenvironment,playing important roles in digestion and absorption,nutrient metabolism,defense against pathogenic infections and regulation of autoimmune diseases.There are complex interactions between parasites residing in the host's gut and the host's gut microbiota,influencing the health of the host's intestine and the onset and progression of related diseases.This article reviews the research progress on the interaction between host intestinal nematodes and intestinal flora,to provide scientific basis for a deeper understanding of the pathogenic mechanisms of related diseases.

关 键 词：肠道菌群 肠道线虫 相互作用 

分 类 号：R383.1[医药卫生—医学寄生虫学]