中国人群良性前列腺增生术后尿路感染危险因素的Meta分析  

Meta-analysis of risk factors of postoperative urinary tract infection in Chinese population with benign prostatic hyperplasia

作　　者：李浩[1] 于莹莹 宋祥伟[1] 张鹤骞 滕立臣 Li Hao;Yu Yingying;Song Xiangwei;Zhang Heqian;Teng Lichen(Department of Urology,the First Hospital of Qiqihar,Qiqihar 161000,China;Department of Urology,Harbin Medical University Cancer Hospital,Harbin 150081,China)

机构地区：[1]齐齐哈尔市第一医院泌尿外科,齐齐哈尔161000 [2]哈尔滨医科大学附属肿瘤医院泌尿外科,哈尔滨150081

出　　处：《国际泌尿系统杂志》2024年第6期993-997,共5页International Journal of Urology and Nephrology

基　　金：哈尔滨医科大学附属肿瘤医院海燕基金(JJMS 2022-14)。

摘　　要：目的运用Meta分析的方法探讨中国人群良性前列腺增生术后尿路感染的危险因素。方法检索PubMed、Embase、Web of Science、中国知网、维普和万方数据库中关于研究中国人群良性前列腺增生术后尿路感染危险因素的文献,检索时限为自建库起至2022年9月。采用Meta分析影响中国人群良性前列腺增生术后尿路感染的危险因素。结果最终纳入28篇相关文献,共涉及7093例良性前列腺增生患者,其中术后合并尿路感染者1132例。Meta分析结果显示,高龄(OR=2.51,95%CI:2.18~2.90,P<0.05)、合并糖尿病(OR=2.92,95%CI:2.58~3.25,P<0.05)、手术时间(OR=3.04,95%CI:2.21~4.17,P<0.05)、术前留置导尿(OR=3.92,95%CI:3.38~4.56,P<0.05)、术后留置导尿管时间(OR=3.63,95%CI:3.16~4.17,P<0.05)、医师为初学者(OR=2.17,95%CI:1.74~2.72,P<0.05)、术前未预防性应用抗菌药物(OR=2.64,95%CI:2.01~3.47,P<0.05)以及术后应用抗菌药物时间≤48 h(OR=2.07,95%CI:1.37~3.15,P<0.05)均是我国良性前列腺增生患者术后发生尿路感染的危险因素。结论中国人群良性前列腺增生术后发生尿路感染涉及多种危险因素,在临床工作中应尽早识别并采取相应干预措施,以免影响患者术后恢复和生活质量。ObjectiveTo explore the risk factors of postoperative urinary tract infection in Chinese population with benign prostatic hyperplasia by Meta-analysis.MethodsDatabases of PubMed,Embase,Web of Science,CNKI,VIP,Wanfang were searched comprehensively to collect literatures on risk factors of postoperative urinary tract infection in Chinese population with benign prostatic hyperplasia.The present study conducted a Meta-analysis to examine the risk factors associated with urinary tract infection following prostatic hyperplasia in the Chinese population.ResultsFinally,a total of 28 pieces of related literatures with 7093 patients were enrolled,including 1132 patients with urinary tract infection after surgery.Meta-analysis indicated that advanced age(OR=2.51,95%CI:2.18-2.90,P<0.05),complicated diabetes(OR=2.92,95%CI:2.58-3.25,P<0.05),duration of surgery(OR=3.04,95%CI:2.21-4.17,P<0.05),preoperative indwelling catheterization(OR=3.92,95%CI:3.38-4.56,P<0.05),duration of postoperative indwelling catheterization(OR=3.63,95%CI:3.16-4.17,P<0.05),physicians for beginners(OR=2.17,95%CI:1.74-2.72,P<0.05),no prophylactic use of antibiotics before surgery(OR=2.64,95%CI:2.01-3.47,P<0.05)and duration of postoperative antibacterial application≤48 hours(OR=2.07,95%CI:1.37-3.15,P<0.05)were risk factors of postoperative urinary tract infection in Chinese population with benign prostatic hyperplasia.ConclusionsPostoperative urinary tract infection in Chinese patients with benign prostatic hyperplasia involves a variety of risk factors.In clinical work,appropriate intervention measures should be identified as soon as possible so as not to affect the postoperative recovery and quality of life of patients.

关 键 词：前列腺增生 尿路感染 年龄分布 糖尿病 

分 类 号：R699.8[医药卫生—泌尿科学]