柳州市单中心泌尿系结石成分及特征性分析  

Analysis of the composition and characteristics of urinary stones in Liuzhou:single-center report

作　　者：彭金健[1] 丁军平[1] 谢华荣 韦智贤 潘思颖 朱建坦[1] 毛洲洲[1] 包鑫明 邱阳 覃万胜 骆厚栋 赵勇[1] Peng Jinjian;Ding Junping;Xie Huarong;Wei Zhixian;Pan Siying;Zhu Jiantan;Mao Zhouzhou;Bao Xinming;Qiu Yang;Qing Wansheng;Luo Houdong;Zhao Yong(Department of Urology,Liuzhou Railway Central Hospital of Liuzhou City(the Affilated Hospital of Guangxi Medical University),Liuzhou 545000,China;Department of Urology,the People′s Hospital of Rongshui Miao Autonomous County,Guangxi,545399,China)

机构地区：[1]柳州市柳铁中心医院(广西医科大学附属柳州医院)泌尿外科,广西545000 [2]融水苗族自治县人民医院泌尿外科,广西545399

出　　处：《国际泌尿系统杂志》2024年第6期1101-1105,共5页International Journal of Urology and Nephrology

基　　金：广西壮族自治区卫生健康委员会计划课题(Z20210943);广西壮族自治区中医药管理局计划课题(GXZYZ20210385)。

摘　　要：目的通过分析广西柳州地区泌尿系结石患者的结石成分,以期为柳州地区尿路结石患者的防治提供临床依据。方法回顾性分析2018年6月至2021年12月柳州市柳铁中心医院收治的579例泌尿系结石患者的临床资料,按照不同年龄将患者分为A组(≤30岁,27例)、B组(31~40岁,79例)、C组(41~60岁,283例)、D组(>60岁,190例),通过红外光谱法对患者的结石成分进行分析,并对结石成分类别、结石成分与性别、年龄及部位之间的关系进行统计学分析。结果结石成分分析结果显示,混合性结石成分明显高于单纯结石成分(P<0.05)。检出率最高的为一水草酸钙,其次是二水草酸钙、碳酸磷灰石、无水尿酸,其中羟基磷灰石、六水磷酸铵镁及其他成分结石所占比例较低。男性患者的无水尿酸结石比例明显高于女性(P<0.05),不同性别患者的其他结石成分比较,差异无统计学意义(P>0.05)。D组患者的无水尿酸结石比例高于其他3组(均P<0.001);B组患者的碳酸磷灰石比例高于C、D组(均P<0.001)。B、C、D组患者的无水尿酸结石比例随着年龄增长而上升(均P<0.05),而二水草酸钙、碳酸磷灰石、羟基磷灰石结石比例随着年龄增长而下降(均P<0.05)。结论广西柳州地区泌尿系结石患者中,中老年发生率较高,男性多于女性,以上尿路结石为主,结石成分均以草酸钙为主,结石成分与性别无关联(无水尿酸结石除外),无水尿酸结石比例随着年龄增长而上升,二水草酸钙、碳酸磷灰石、羟基磷灰石结石比例随着年龄增长而下降。ObjectiveTo provide clinical reference for the prevention and treatment of urinary calculi in Liuzhou by analyzing the component of urinary calculi.MethodsThe clinical data of 579 patients with urinary calculi admitted to Liutie Central Hospital between June 2018 and December 2021 were retrospectively analyzed.Based on age,the patients were categorized into four groups:group A(≤30 years old,27 cases),group B(31-40 years old,79 cases),group C(41-60 years old,283 cases),and group D(>60 years old,190 cases).Infrared spectroscopy was utilized to analyze the composition of the calculi,and statistical analysis was conducted to examine the relationship between calculi components,gender,age,and location.ResultsThe findings revealed a significantly higher proportion of mixed stones compared to simple stones(P<0.05).The detection rate was highest for calcium oxalate monohydrate,followed by calcium oxalate dihydrate and carbonate apatite,while anhydrous uric acid had a lower detection rate.Hydroxyapatite,magnesium ammonium phosphate hexahydrate and other components accounted for a small proportion of stones.The proportion of anhydrous uric acid stones in males was significantly higher than that in females(P<0.05).There were no statistically significant differences observed between genders with respect to other stone components(P>0.05).The proportion of anhydrous uric acid in group D was higher than that in the other three groups(all P<0.001).The proportion of carbonate apatite in group B was higher than that in group C and D(all P<0.001).The proportion of anhydrous uric acid stones in groups B,C and D increased with age(all P<0.05),while the proportion of calcium oxalate dihydrate,carbonate apatite and hydroxyapatite stones decreased with age(all P<0.05).ConclusionsIn Liuzhou,Guangxi,the prevalence of urinary calculi was higher among middle-aged and elderly individuals,with a significantly higher incidence in males compared to females.Urinary calculi were predominantly found in the upper urinary tract.The main component o

关 键 词：泌尿系疾病 结石 柳州 

分 类 号：R691.4[医药卫生—泌尿科学]