2018—2022年张家港市围产儿出生缺陷情况分析  

Analysis of birth defects in perinatal infants in Zhangjiagang City from 2018 to 2022

作　　者：刘光辉 李丽多 LIU Guanghui;LI Liduo(Zhangjiagang Maternal and Child Health Center,Zhangjiagang,Jiangsu 215600,China)

机构地区：[1]张家港市妇幼保健所,江苏张家港215600

出　　处：《中国优生与遗传杂志》2024年第10期2166-2169,共4页Chinese Journal of Birth Health & Heredity

摘　　要：目的分析张家港市围产儿缺陷的发生率及发生顺位,为张家港市出生缺陷防治工作提供有效参考依据。方法2018年1月至2022年12月回顾性分析张家港市助产机构内出生的妊娠满28周至出生后7天的围产儿(包括活产、死胎和死产)缺陷的发生率及发生顺位。结果张家港市2018—2022年全市共计围产儿数44311例,其中出生缺陷儿311例,出生缺陷总的发生率为7.02‰,2018—2022年每年围产儿出生缺陷发生率依次为4.15‰、4.46‰、5.66‰、11.15‰及12.94‰。311例出生缺陷儿中,总体出生缺陷前5顺位分别为先天性心脏病、多指(趾)、小耳或外耳畸形、总唇裂和马蹄内翻足。2018—2022年张家港市产妇年龄<20岁、20~24岁、25~29岁、30~34岁及≥35岁所生围产儿出生缺陷发生率为7.82‰、7.52‰、6.81‰、6.18‰和9.79‰。结论2018—2022年张家港市围产儿出生缺陷发生率为7.02‰,总体出生缺陷前5顺位分别为先天性心脏病、多指(趾)、小耳或外耳畸形、总唇裂和马蹄内翻足,其中先天性心脏病的发生率呈现明显上升趋势,年龄≥35岁产妇所生新生儿出生缺陷率最高,其次是年龄<20岁。Objective To analyze the incidence and ranking of perinatal defects in Zhangjiagang City and provide effectivereference for the prevention and control of birth defects in the local area. Methods A retrospective analysis was conductedon the incidence and ranking of defects in perinatal infants (including live birth, stillbirth, and fetal deaths) born at 28weeks of gestation to 7 days after birth in the city’s maternity institutions from January 2018 to December 2022. Results From2018 to 2022, there were a total of 44311 perinatal babies in Zhangjiagang City, including 311 cases of birth defects. Theoverall incidence rate of birth defects was 7.02‰. The annual incidence rates of perinatal birth defects from 2018 to 2022 were4.15‰, 4.46‰, 5.66‰, 11.15‰, and 12.94‰, respectively. Among the 311 cases of birth defects, the top 5 defects were congenitalheart disease, polydactyly, microtia or external ear malformation, total cleft lip, and talipes equinovarus. The incidence ratesof birth defects in perinatal infants born to mothers aged <20 years, 20-24 years old, 25-29 years old, 30-34 years old, and ≥35 yearsold in Zhangjiagang City from 2018 to 2022 were 7.82‰, 7.52‰, 6.81‰, 6.18‰, and 9.79‰. Conclusion From 2018 to 2022, theincidence rate of perinatal birth defects in Zhangjiagang City was 7.02‰. The top 5 defects were congenital heart disease, polydactyly,microtia or external ear malformation, total cleft lip, and talipes equinovarus. The incidence rate of congenital heartdisease showed a significant upward trend, and the incidence rate of birth defects in mothers aged ≥ 35 years old is the highest,followed by those aged<20.

关 键 词：围产儿 出生缺陷 构成比 

分 类 号：R174[医药卫生—妇幼卫生保健]