机构地区:[1]江苏省宿迁市中西医结合医院,江苏宿迁223800 [2]江苏省苏州市中西医结合医院,江苏苏州215100
出 处:《中国药业》2024年第23期91-94,共4页China Pharmaceuticals
基 金:江苏省中医药科技发展计划项目[Z2019080];江苏省宿迁市中医药科技项目[YB202206]。
摘 要:目的探讨基于损伤韧带形态学的民间单方扭伤散配合纸夹板固定治疗急性踝关节扭伤的临床疗效。方法选取江苏省宿迁市中西医结合医院联合苏州市中西医结合医院2022年1月至2023年7月收治的急性踝关节扭伤患者102例,按随机数字表法分为对照组和试验组,各51例。在常规康复训练基础上,对照组患者予纸夹板+金黄散治疗,试验组患者予纸夹板+扭伤散治疗,两组患者均持续治疗14 d。结果试验组的总有效率为82.35%,显著高于对照组的60.78%(P<0.05)。治疗后,两组患者的中医证候(疼痛肿胀、跛行步态、皮下瘀斑、关节活动受限)积分均显著降低(P<0.05),且试验组均显著低于对照组(P<0.05);两组患者的美国足踝外科功能评分量表(AOFAS)评分均显著升高(P<0.05),视觉模拟评分法(VAS)、肿胀评分量表的评分均显著降低(P<0.05),且试验组均显著优于对照组(P<0.05);两组患者的损伤韧带形态学指标(受伤韧带和健侧韧带的长度、宽度、厚度差值)均显著降低(P<0.05),且试验组均显著低于对照组(P<0.05);两组患者的炎性因子白细胞介素-6、肿瘤坏死因子-α、超敏C反应蛋白水平均显著降低(P<0.05),且试验组均显著低于对照组(P<0.05)。结论基于损伤韧带形态学的民间单方扭伤散配合纸夹板固定治疗急性踝关节扭伤的临床疗效良好,可恢复患者的关节功能与损伤韧带形态学,减轻疼痛程度,并改善炎性因子水平。Objective To investigate the clinical efficacy of folk unilateral Niushang Powder combined with paper splint fixation based on the injury ligament morphology in the treatment of acute ankle sprains.Methods A total of 102 patients with acute ankle sprain admitted to the Suqian Hospital of Integrated Traditional Chinese and Western Medicine from January 2022 to July 2023 were selected and randomly divided into the control group and the test group by the random number table method,with 51 cases in each group.On the basis of routine rehabilitation training,the patient in the control group were treated with paper splint fixation combined with Jinhuang Powder,while the patients in the test group were treated with paper splint fixation combined with Niushang Powder.Both groups were treated continuously for 14 d.Results The total effective rate in the test group was 82.35%,which was significantly higher than 60.78%in the control group(P<0.05).After treatment,the scores of traditional Chinese medicine(TCM)symptoms(pain and swelling,limping gait,subcutaneous bruising,limited joint movement)in the two groups significantly reduced(P<0.05),and those in the test group were significantly lower than those in the control group(P<0.05).The American Foot and Ankle Surgical Function Scale(AOFAS)scores in the two groups significantly increased(P<0.05),while the Visual Analog Scale(VAS)and Swelling Scale scores in the two groups significantly decreased(P<0.05),and those in the test group were significantly better than those in the control group(P<0.05).The morphological indicators of the injured ligaments(the difference in length,width,and thickness between the injured ligament and the healthy ligament)in the two groups significantly reduced,and those in the test group were significantly lower than those in the control group(P<0.05).The levels of inflammatory factors interleukin-6,tumor necrosis factor-α,and high-sensitivity C-reactive protein in the two groups significantly reduced(P<0.05),and those in the test group were significan
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