清热燥湿解毒兼护阴方治疗溃疡性结肠炎患者的效果  

Effects of Qingre Zaoshi Jiedu Huyin Decoction in Patients with Ulcerative Colitis

作　　者：吴冬梅 牛明了 甄欢欢 WU Dongmei;NIU Mingliao;ZHEN Huanhuan(Department of Proctology,Henan Provincial Hospital of TCM(the Second Affiliated Hospital of Henan University of Chinese Medicine),Zhengzhou 450000,China)

机构地区：[1]河南省中医院(河南中医药大学第二附属医院)肛肠科,河南郑州450000

出　　处：《河南医学研究》2024年第22期4165-4168,共4页Henan Medical Research

基　　金：河南省中医药科学研究专项课题(2023ZY2083)。

摘　　要：目的探讨清热燥湿解毒兼护阴方治疗溃疡性结肠炎(UC)患者的效果。方法选取2019年2月至2021年2月在河南省中医院就诊的86例UC患者,以随机数表法分为观察组(43例)和对照组(43例),对照组接受美沙拉嗪治疗,观察组接受清热燥湿解毒兼护阴方联合美沙拉嗪治疗。比较两组治疗总有效率、中医证候评分、Bristol粪便性状量表(BSFS)评分、炎症性肠病简明健康量表(SHS)评分。结果观察组总有效率高于对照组(P<0.05);观察组治疗后中医证候评分、便秘症状评分表(KESS)、SHS评分低于对照组,BSFF评分高于对照组(P<0.05)。结论清热燥湿解毒兼护阴方辅助美沙拉嗪治疗溃疡性结肠炎患者的效果较好,可改善患者症状和大便性状。Objective To explore curative effect of Qingre Zaoshi Jiedu Huyin Decoction in patients with ulcerative colitis(UC).Methods According to random number table method,86 patients with UC treated in Henan Provincial Hospital of TCM between February 2019 and February 2021 were divided into control group(43 cases,mesalazine)and observation group(43 cases,mesalazine and Qingre Zaoshi Jiedu Huyin Decoction).The total response rates of treatment,scores of TCM syndromes,Bristol stool form scale(BSFS)and inflammatory bowel disease short health scale(SHS)in the two groups were compared.Results The total response rate was higher in observation group than control group(P<0.05).After treatment,scores of TCM syndromes,knowles eccersley scott symptom(KESS)and SHS were lower in observation group than control group,while BSFS score was higher in observation group(P<0.05).Conclusion Curative effect of Qingre Zaoshi Jiedu Huyin Decoction combined with mesalazine is good in UC patients,which can improve symptoms and stool property.

关 键 词：溃疡性结肠炎 湿热蕴脾证 清热解毒 辨证论治 

分 类 号：R256.34[医药卫生—中医内科学]