经皮机械血栓清除术与导管接触溶栓治疗急性髂股静脉血栓形成的对照研究  

Comparative Study of Percutaneous Mechanical Thrombectomy and Catheter-directed Thrombolysis in the Treatment of Acute Iliofemoral Deep Venous Thrombosis

作　　者：刘俊 阳普根 欧阳飞兰 欧阳亮远 刘智鹏 吴静 刘海兵 LIU Jun;YANG Pugen;OUYANG Feilan;OUYANG Liangyuan;LIU Zhipeng;WU Jing;LIU Haibing(Department of Vascular Surgery,Yichun People's Hospital,Yichun 336000,China;不详)

机构地区：[1]宜春市人民医院血管外科,江西宜春336000

出　　处：《中国医学创新》2024年第28期11-15,共5页Medical Innovation of China

基　　金：宜春市指导性科技计划项目(2022ZDJH6180)。

摘　　要：目的:对比研究经皮机械血栓清除术(PMT)与导管接触溶栓(CDT)治疗急性髂股静脉血栓(IFDVT)的效果。方法:选取2019年6月—2022年4月于宜春市人民医院(北院)进行治疗的82例急性IFDVT患者,以随机数字表法分为PMT组(采取PMT治疗)和CDT组(采取CDT治疗),每组41例。比较两组静脉通畅评分、血栓清除率、尿激酶用量、溶栓时间、住院天数及并发症发生情况。结果:两组血栓清除率、治疗后静脉通畅评分比较,差异均无统计学意义(P>0.05)。PMT组尿激酶用量少于CDT组,溶栓时间及住院天数均短于CDT组(P<0.05)。两组血栓后综合征(PTS)发生率及术后并发症发生率比较,差异均无统计学意义(P>0.05)。结论:PMT与CDT治疗效果均较好,但PMT具有溶栓药物用量少、溶栓时间短、住院天数短的优势。Objective:To compare the effects of percutaneous mechanical thrombectomy(PMT)and catheter-directed thrombolysis(CDT)in the treatment of acute iliofemoral deep venous thrombosis(IFDVT).Method:A total of 82 patients with acute IFDVT who were treated in Yichun People's Hospital(North Hospital)from June 2019 to April 2022 were selected and divided into PMT group(received PMT treatment)and CDT group(received CDT treatment)by random number table method,with 41 cases in each group.Venous patency scores,thrombus clearance rate,Urokinase dosage,thrombolytic time,hospitalization days and complications were compared between two groups.Result:There were no significant differences in thrombus clearance rate and venous patency scores between two groups(P>0.05).The dosage of Urokinase in PMT group was lower than that in CDT group,and the thrombolytic time and hospitalization days were shorter than those in CDT group(P<0.05).There were no significant differences in the incidence of post-thrombotic syndrome(PTS)and postoperative complications between two groups(P>0.05).Conclusion:Both PMT and CDT have good therapeutic effect,but PMT has the advantages of less dosage of thrombolytic drug,short thrombolytic time and short hospitalization days.

关 键 词：经皮机械血栓清除术 导管接触溶栓 急性髂股静脉血栓 尿激酶 血栓清除率 溶栓时间 

分 类 号：R654.4[医药卫生—外科学]