机构地区:[1]上饶市妇幼保健院生殖科,江西上饶334000
出 处:《中国医学创新》2024年第28期65-69,共5页Medical Innovation of China
摘 要:目的:探究盆底电刺激联合人工周期疗法在薄型子宫内膜中的疗效及对子宫内膜容受性的影响。方法:将2019年9月—2022年9月上饶市妇幼保健院的115例薄型子宫内膜患者根据随机数字表法分为对照组(57例)和观察组(58例)。对照组采用人工周期疗法治疗,观察组则采用盆底电刺激联合人工周期疗法治疗。比较两组的薄型子宫内膜治疗总有效率、妊娠率、活产率、治疗前后的子宫内膜厚度、月经量及子宫内膜容受项目。子宫内膜容受项目包括子宫内膜下血流灌注指标[搏动指数(PI)及阻力指数(RI)]、子宫内膜血管化血流参数[血管化指数(VI)、血流指数(FI)、血管化血流指数(VFI)]及子宫内膜血流分型。结果:观察组的薄型子宫内膜治疗总有效率、妊娠率及活产率均显著高于对照组,差异均有统计学意义(P<0.05)。治疗前,两组的子宫内膜厚度、月经量及子宫内膜容受项目比较,差异均无统计学意义(P>0.05);治疗3个月后,观察组的子宫内膜厚度、月经量及子宫内膜血管化血流参数均显著高于对照组,子宫内膜下血流灌注指标均显著低于对照组,子宫内膜血流分型显著优于对照组,差异均有统计学意义(P<0.05)。结论:盆底电刺激联合人工周期疗法在薄型子宫内膜中的疗效较好,且可显著改善患者的子宫内膜容受性,因此在薄型子宫内膜患者中的应用价值相对更高。Objective:To investigate the effect of pelvic floor electric stimulation combined with artificial cycle therapy in patients with thin endometrium and its influence for endometrial receptivity.Method:A total of 115 patients with thin endometrium in Shangrao Maternal and Child Health Hospital from September 2019 to September 2022 were divided into control group(57 cases)and observation group(58 cases)according to the random number table method.The control group was treated with artificial cycle therapy,the observation group was treated with pelvic floor electric stimulation combined with artificial cycle therapy.Then the total effective rates of thin endometrium treatment,pregnancy rates,live birth rates,endometrial thickness,menstrual blood volume,endometrial receptivity items before and after the treatment of two groups were compared.The endometrial receptivity items included endometrial blood flow perfusion indexes[pulsitility index(PI)and resistance index(RI)],endometrial vascularization-blood flow parameters[vascularization index(VI),flow index(FI)and vascularization flow index(VFI)]and endometrial blood flow classifications.Result:The total effective rate of thin endometrium treatment,pregnancy rate and live birth rate of observation group were significantly higher than those of control group,the differences were statistically significant(P<0.05).Before the treatment,the endometrial thickness,menstrual blood volume and endometrial receptivity items of two groups were compared,the differences were not statistically significant(P>0.05);the endometrial thickness,menstrual blood volume and endometrial vascularization-blood flow parameters of observation group at three months after treatment were significantly higher than those of control group,the endometrial blood flow perfusion indexes were significantly lower than those of control group,the endometrial blood flow classifications was significantly better than that of control group,the differences were statistically significant(P<0.05).Conclusion:The effect of p
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