不同类型性早熟患儿应用子宫、卵巢容积测量结合性激素E_(2)水平检测的价值分析  

Value Analysis of Uterus and Ovary Volume Measurement Combined with Sex Hormone E_(2) Level Detection in Children with Different Types of Precocious Puberty

作　　者：戴理平 郭艳 李志强 DAI Liping;GUO Yan;LI Zhiqiang(Department of Ultrasound Medicine,Jiangxi Province Integrated Traditional Chinese and Western Medicine Hospital,Nanchang 330003,China;不详)

机构地区：[1]江西省中西医结合医院超声医学科,江西南昌330003

出　　处：《中国医学创新》2024年第28期166-169,共4页Medical Innovation of China

摘　　要：目的:探讨不同类型性早熟患儿应用子宫、卵巢容积测量结合性激素雌二醇(E_(2))水平检测的价值。方法:选取2022年1月—2023年12月江西省中西医结合医院收治的84例性早熟患儿作为研究对象,根据性早熟类型分为中枢性组(n=63)和外周性组(n=21)。对比两组子宫长径、横径及容积,卵巢长径、横径及容积,以及E_(2)、黄体生成素(LH)、促卵泡激素(FSH)水平,并采用受试者操作特征(ROC)曲线分析子宫、卵巢容积测量结合E_(2)检测在中枢性性早熟中的诊断价值。结果:中枢性组子宫及卵巢长径、横径均长于外周性组,子宫容积、卵巢容积均大于外周性组,差异均有统计学意义(P<0.05);中枢性组E_(2)、LH、FSH水平均较外周性组高,差异均有统计学意义(P<0.05);ROC曲线显示,子宫容积、卵巢容积、E_(2)水平单一及联合检测诊断中枢性性早熟的曲线下面积(AUC)分别为0.781、0.725、0.832、0.901,三项联合的AUC高于各单项指标的AUC。结论:子宫、卵巢容积测量结合E_(2)水平诊断中枢性性早熟具有较高价值。Objective:To explore the value of uterine and ovarian volume measurement combined with sex hormone estradiol(E_(2))level detection in children with different types of precocious puberty.Method:A total of 84 children with precocious puberty admitted to Jiangxi Province Integrated Traditional Chinese and Western Medicine Hospital from January 2022 to December 2023 were selected as the study objects,and they were divided into central group(n=63)and peripheral group(n=21)according to the type of precocious puberty.The length diameter,transverse diameter,anteroposterior diameter and volume of uterus,the length diameter,transverse diameter and volume of ovary,and the levels of E_(2),luteinizing hormone(LH)and follicle-stimulating hormone(FSH)were compared between two groups.The diagnostic value of uterus and ovarian volume measurement combined with E_(2) detection in central precocious puberty were analyzed by receiver operating characteristic(ROC)curve.Result:The length and transverse diameter of uterus and ovary in the central group were longer than those in the peripheral group,and the volume of uterus and ovary were larger than those in the peripheral group,the differences were statistically significant(P<0.05).The levels of E_(2),LH and FSH in central group were higher than those in peripheral group,the differences were statistically significant(P<0.05).ROC curve showed that the area under the curve(AUC)for the diagnosis of central precocious puberty by single detection and combined detection of uterine volume,ovarian volume and E_(2) level in the diagnosis of central precocious puberty were 0.781,0.725,0.832 and 0.901,respectively,and the AUC value of the three combined was higher than that of each single index.Conclusion:The measurement of uterine and ovarian volume combined with E_(2) level has high value in the diagnosis of central precocious puberty.

关 键 词：性早熟 子宫容积 卵巢容积 性激素 雌二醇 

分 类 号：R725.8[医药卫生—儿科]