多学科协作诊疗持续药学监护系统在抗感染治疗患者中的应用  

Application of the multi-disciplinary treatment-based continuous pharmaceutical care system in patients undergoing anti-infection treatment

作　　者：谭瑞[1] 邹婷婷[1] 孙伟[2] 彭礼波 苟静惠 TAN Rui;ZOU Tingting;SUN Wei;PENG Libo;GOU Jinghui(Dept.of Pharmacy,Banan Hospital Affiliated to Chongqing Medical University,Chongqing 401320,China;Dept.of Infectious Hepatology,Banan Hospital Affiliated to Chongqing Medical University,Chongqing 401320,China;Dept.of Critical Care Medicine,Banan Hospital Affiliated to Chongqing Medical University,Chongqing 401320,China;Dept.of Pharmacy,the Third Affiliated Hospital of Chongqing Medical University,Chongqing 401120,China)

机构地区：[1]重庆医科大学附属巴南医院药剂科,重庆401320 [2]重庆医科大学附属巴南医院感染肝病科,重庆401320 [3]重庆医科大学附属巴南医院重症医学科,重庆401320 [4]重庆医科大学附属第三医院药剂科,重庆401120

出　　处：《中国药房》2024年第23期2936-2940,共5页China Pharmacy

基　　金：重庆市科卫联合医学科研项目(No.2022QNXM003)。

摘　　要：目的探索多学科协作诊疗(MDT)持续药学监护系统在抗感染治疗患者中的应用效果。方法本研究团队通过创新研发一套MDT持续药学监护系统,将其应用于因感染经MDT后的抗感染治疗病例,以此实现持续用药监护模式创新。采用回顾性分析方法,收集重庆医科大学附属巴南医院2021年1-10月重症医学科经传统抗感染MDT的150例患者为对照组,2022年1-10月重症医学科因抗感染治疗实行MDT持续药学监护系统管理的130例患者为干预组。比较两组患者一般资料、持续跟踪管理情况、抗感染治疗转归情况、药品不良反应发生情况、抗菌药物管理相关指标以及相关医务人员对临床药师药学服务的满意度。结果两组患者一般资料比较,差异均无统计学意义(P>0.05)。干预组患者持续跟踪管理比例明显高于对照组(P<0.01);且两组持续跟踪管理发起人员、发起原因比较,差异均有统计学意义(P<0.05)。干预组抗感染治疗转归情况优于对照组,抗菌药物管理相关指标(总住院时间、抗菌药物使用时间、药品总费用、抗菌药物使用量)低于对照组,医务人员综合满意度高于对照组,差异均有统计学差异(P<0.05)。两组患者不良反应发生情况、抗菌药物费用差异均无统计学意义(P>0.05)。结论本系统应用于经MDT后的抗感染治疗患者,可实现以临床药师为核心的持续多学科跟踪管理,有利于提高MDT团队随访效率,提升临床药师药学服务质量,改善治疗结局,促进临床合理使用抗菌药物。OBJECTIVE To explore the application effects of the multi-disciplinary treatment(MDT)-based continuous pharmaceutical care system in patients undergoing anti-infection treatment.METHODS This research team innovatively developed an MDT continuous pharmaceutical care system,which was applied to cases of anti-infection treatment following MDT due to infection,aiming to innovate the continuous medication supervision model.A retrospective analysis method was used to collect data from 150 patients in the intensive care unit who underwent conventional anti-infection MDT consultations from January to October 2021 in Banan Hospital Affiliated to Chongqing Medical University,serving as the control group,and 130 patients in the intensive care unit who were under the MDT continuous pharmaceutical care system from January to October 2022 were selected as the intervention group.The general information of the patients,the information continuous tracking management,the outcomes of antiinfection treatment,adverse drug reactions,antibacterial drug management indicators,and the degree of satisfaction of relevant medical staff with the clinical pharmacists’pharmaceutical services were compared between the two groups.RESULTS Comparison of general information between the two groups showed no statistically significant differences(P>0.05).The proportion of continuous tracking management in the intervention group was significantly higher than in the control group(P<0.01),and the differences in the initiators and reasons for continuous tracking management between the two groups were statistically significant(P<0.05).The intervention group had better outcomes in anti-infection treatment compared to the control group(P<0.05).The antibacterial drug management indicators(total length of hospital stay,duration of antibacterial drug use,total drug costs,and amount of antibacterial drugs used)in the intervention group were significantly lower than in the control group,while overall degree of satisfaction among medical staff was significantly h

关 键 词：多学科协作诊疗 持续药学监护系统 药学服务 抗菌药物 跟踪管理 满意度 

分 类 号：R95[医药卫生—药学]