胎儿心腔内注射氯化钾联合羊膜腔内注射利凡诺终止中期妊娠临床观察  

Clinical Efficacy of Intra-Cardiac Injection of Potassium Chloride Combined with Intra-Amniotic Injection of Rivanol in Terminating Mid-Term Pregnancy in Fetuses

作　　者：许晓艳 左莉 XU Xiaoyan;ZUO Li(Department of Obstetrics,Liangjiang New District People's Hospital,Chongqing,China 401120)

机构地区：[1]重庆市两江新区人民医院产科,重庆401120

出　　处：《中国药业》2024年第S02期40-42,共3页China Pharmaceuticals

摘　　要：目的探讨胎儿心腔内注射氯化钾联合羊膜腔内注射利凡诺终止中期妊娠的临床效果。方法选取医院产科2022年1月至2023年12月收治的需要终止妊娠的中期妊娠孕妇80例,根据引产方式的不同分为对照组和观察组,各40例。对照组予羊膜腔内注射利凡诺终止妊娠,观察组在对照组基础上联合胎儿心腔内注射氯化钾终止妊娠。比较两组产妇的宫缩发动时长、终止妊娠需要时间、产后出血状态、住院时间和药品不良反应。引产3个月后进行回访调查,比较产妇月经恢复用时。结果两组产妇的宫缩发动时长、终止妊娠需要时间、产后出血量、住院时间、月经恢复时间均无显著差异(P>0.05);观察组的清宫率显著低于对照组,清宫总有效率显著高于对照组(P<0.05);观察组不良反应发生率显著低于对照组(P<0.05)。结论胎儿心腔内注射氯化钾联合羊膜腔内注射利凡诺终止中期妊娠的临床效果良好,能降低清宫率,提高清宫效果,且安全性较好。Objective To investigate the clinical effect of intrauterine injection of potassium chloride combined with intrauterine injection of rivanol in terminating mid-term pregnancy in fetuses.Methods A total of 80 mid-term pregnant women who needed to terminate their pregnancies and were admitted to the obstetrics department of the hospital from January 2022 to December 2023 were selected and divided into the control group and the observation group based on different induction methods,with 40 cases in each group.The control group was given intraperitoneal injection of rivanol to terminate pregnancy,while the observation group was given intraperitoneal injection of potassium chloride in addition to the control group to terminate pregnancy.The duration of uterine contractions,the time required to terminate pregnancy,postpartum bleeding status,hospital stay,and adverse drug reactions between two groups were compared.Follow up survey will be conducted 3 months after induced abortion to compare the recovery time of menstruation for the parturient.Results There were no significant differences in the duration of uterine contractions,the time required to terminate pregnancy,postpartum bleeding,hospitalization time,and menstrual recovery time between the two groups(P>0.05).The curettage rate in the observation group was significantly lower than that in the control group,and the total effective rate of curettage was significantly higher than that in the control group(P<0.05).The incidence of the incidence of adverse reactions in the observation group was significantly lower than that in the control group(P<0.05).Conclusion Injecting potassium chloride into the fetal heart cavity combined with injection of rivanol into the amniotic cavity to terminate mid-term pregnancy has good clinical efficacy,which can reduce the curettage rate,improve the curettage effect,and has good safety.

关 键 词：胎儿心腔内注射氯化钾 羊膜腔内注射利凡诺 终止中期妊娠 

分 类 号：R969.4[医药卫生—药理学] R984[医药卫生—药学]