银杏叶提取物注射液联合胞磷胆碱钠片对急性脑梗死患者神经功能的影响  

Effect of Ginkgo Biloba Extract Injection Combined with Sodium Phosphatidylcholine Tablets on Neurological Function in Patients with Acute Cerebral Infarction

作　　者：黄晶 HUANG Jing(Guangming Traditional Chinese Medicine Hospital of Pudong New Area,Shanghai,China 201303)

机构地区：[1]上海市浦东新区光明中医医院,上海201303

出　　处：《中国药业》2024年第S02期45-47,共3页China Pharmaceuticals

摘　　要：目的探讨银杏叶提取物注射液联合胞磷胆碱钠片对急性脑梗死患者神经功能的影响。方法选取医院2023年1月至9月收治的急性脑梗死患者100例,按治疗方案的不同分为对照组和观察组,各50例。对照组患者予胞磷胆碱钠片,观察组患者在对照组基础上加用银杏叶提取物注射液,均持续治疗14 d。结果观察组临床总有效率为98.00%,显著高于对照组的82.00%(P<0.05)。观察组患者的神经生长因子(NGF)、脑源性神经营养因子(BDNF)均显著高于对照组(P<0.05),血清单核细胞趋化蛋白-1(MCP-1)、血清人神经胶质纤维酸性蛋白(GFAP)均显著低于对照组(P<0.05)。结论银杏叶提取物注射液结合胞磷胆碱钠片治疗急性脑梗死的临床疗效良好,有助于降低患者的炎性因子水平,促进神经功能恢复。Objective To investigate the effect of Ginkgo Biloba Extract Injection combined with Sodium Phosphatidylcholine Tablets on neurological function in patients with acute cerebral infarction.Methods A total of 100 patients with acute cerebral infarction admitted to the hospital from January to September 2023 were selected and divided into the control group and the observation group according to different treatment measures,with 50 cases in each group.The control group received Sodium Phosphatidylcholine Tablets,while the observation group received Ginkgo Biloba Extract Injection in addition to the control group.Both groups were treated continuously for 14 d.Results The total clinical effective ratein the observation group was 98.00%,which was significantly higher than 82.00%in the control group(P<0.05).The levels of nerve growth factor(NGF)and brain-derived neurotrophic factor(BDNF)in the observation group were significantly higher than those in the control group(P<0.05),while the levels of serum monocyte chemoattractant protein-1(MCP-1)and serum human glial fibrillary acidic protein(GFAP)were significantly lower than those in the control group(P<0.05).Conclusion Ginkgo Biloba Extract Injection combined with Sodium Phosphatidylcholine Tablets in the treatment of acute cerebral infarction has good clinical efficacy,which helps to reduce the levels of inflammatory factors in patients and promote the recovery of neurological function.

关 键 词：银杏叶提取物注射液 胞磷胆碱钠片 急性脑梗死 神经功能 

分 类 号：R932[医药卫生—生药学] R285.6[医药卫生—药学]