输血不良反应发生的现状分析及影响因素调查  

Current Situation Analysis of Adverse Blood Transfusion Reactions and Investigation of Influencing Factors

作　　者：张媚琰 顾屏 李婷婷[1] ZHANG Meiyan;GU Ping;LI Tingting(Department of Laboratory,Suzhou Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine,Suzhou 215000,China;不详)

机构地区：[1]南京中医药大学附属苏州市中医医院检验科,江苏苏州215000 [2]南通市第二人民医院检验科,江苏南通226002

出　　处：《中国医学创新》2024年第31期175-178,共4页Medical Innovation of China

摘　　要：目的:分析输血不良反应发生的现状及影响因素。方法:选择200例于南京中医药大学附属苏州市中医医院和南通市第二人民医院2019年1月—2023年12月接受输血治疗的原发血液疾病患者作为对象进行研究,调查患者输血不良反应发生情况,将发生输血不良反应患者作为发生组,未发生输血不良反应的作为未发生组,收集患者相关资料进行分组研究对比,通过单因素、logistic多因素分析输血不良反应发生的主要危险因素。结果:200例患者中,发生输血反应患者有74例,不良反应发生率为37.00%,其中发热反应22例,过敏反应43例,胸闷4例,其他5例;两组性别、年龄、血型对比差异均无统计学意义(P>0.05);发生组输血史、原发血液疾病史、过敏史比例高于未发生组,差异均有统计学意义(P<0.05);经多因素logistic回归分析显示,输血史、过敏史、原发血液疾病史是为输血不良反应发生的危险因素(P<0.05)。结论:发热、过敏反应是原发血液疾病患者主要且常见的输血不良反应,输血史、原发血液疾病史及过敏史是输血患者发生不良反应主要因素。Objective:To analyze the current situation of adverse blood transfusion reactions and the influencing factors.Method:A total of 200 patients with primary blood disease who received blood transfusion treatment in Suzhou Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine and the Second People's Hospital of Nantong from January 2019 to December 2023 were selected as subjects to investigate the occurrence of adverse blood transfusion reactions.Patients with adverse blood transfusion reactions were selected as the occurrence group and those without adverse blood transfusion reactions were selected as the without occurrence group,and relevant patient data were collected for grouping and comparison.The main risk factors of adverse blood transfusion reactions were analyzed by univariate and logistic regression analysis.Result:Among the 200 patients,74 patients had blood transfusion reactions,and the incidence of adverse reactions was 37.00%,including fever reaction in 22 cases,allergic reaction in 43 cases,chest tightness in 4 cases and other 5 cases.There were no significant differences in gender,age and blood type between the two groups(P>0.05).The rates of blood transfusion history,allergy history and primary blood disease history in the occurrence group were higher than those in the without occurrence group(P<0.05).Multivariate logistic regression analysis showed that blood transfusion history,allergy history and primary blood disease history were the risk factors for adverse blood transfusion reactions(P<0.05).Conclusion:The main adverse reactions of blood transfusion in patients with primary blood disease are fever and anaphylaxis,and the history of blood transfusion,anaphylaxis and primary blood disease are the main risk factors leading to the occurrence of adverse reactions of blood transfusion.

关 键 词：输血不良反应 现状分析 影响因素 输血史 过敏史 原发血液疾病史 

分 类 号：R457.1[医药卫生—治疗学]