止血带诱发缺血再灌注损伤的预防治疗研究进展  

Research Progress on Prevention and Treatment of Tourniquet Induced Ischemia Reperfusion Injury

作　　者：姚慧杰 赵涛 李希明[1,4] YAO Huijie;ZHAO Tao;LI Ximing(School of Anesthesiology,Shandong Second Medical University,Weifang 261053,China;不详)

机构地区：[1]山东第二医科大学麻醉学院,山东潍坊261053 [2]日照市中医医院麻醉科,山东日照276800 [3]日照市人民医院麻醉科,山东日照276826 [4]临沂市人民医院麻醉科,山东临沂276034

出　　处：《中国医学创新》2024年第29期184-188,共5页Medical Innovation of China

摘　　要：止血带是骨科手术常用的止血设备,应用于四肢手术,可以维持清晰、无血的手术视野,减少失血量,加速康复。同时,止血带的使用会给患者带来许多不良反应,包括炎症反应、缺血再灌注损伤(ischemia reperfusion injury,IRI)等,严重甚至危及生命。本文对止血带诱发IRI的机制、影响及预防治疗措施做了总结与探讨,旨在为预防治疗止血带诱发IRI提供新的理论依据。Tourniquet is a hemostatic device commonly used in orthopedic surgery.It can maintain a clear and bloodless surgical field of view,reduce blood loss and accelerate recovery.At the same time,the use of tourniquet would cause a lot of adverse reactions to patients,including inflammation and ischemia reperfusion injury(IRI),which is serious or even life-threatening.This paper summarizes and discusses the mechanism,influence and preventive treatment measures of tourniquet induced IRI,aiming to provide a new theoretical basis for the prevention and treatment of tourniquet induced IRI.

关 键 词：止血带 缺血再灌注损伤 缺血预处理 

分 类 号：R614[医药卫生—麻醉学]