免疫抗体与盆腔炎性疾病的相关性分析  

Correlation analysis of immune antibodies with pelvic inflammatory diseases

作　　者：梁芳 谢翰林 刘俨兴 韦佩祺 盛正和[1] 翁映虹[1] 覃景春 曾健[1] 韦楚楚 宋丹 刘溯章[1] 朱媛月[1] 吕梓瑜 LIANG Fang;XIE Hanlin;LIU Yanxing;WEI Peiqi;SHENG Zhenghe;WENG Yinghong;QIN Jingchun;ZENG Jian;WEI Chuchu;SONG Dan;LIU Suzhang;ZHU Yuanyue;LYU Ziyu(Liuzhou People’S Hospital,Liuzhou 545006,China;Graduate School,Guangxi University of Chinese Medicine,Nanning 530200,China)

机构地区：[1]柳州市人民医院,545006 [2]广西中医药大学研究生院,南宁530200

出　　处：《免疫学杂志》2024年第5期480-484,共5页Immunological Journal

基　　金：广西柳州市科技攻关项(2020NBAB0805);广西柳州市自筹课题(GXZYB20230519)。

摘　　要：目的回顾性分析免疫抗体与盆腔炎性疾病(pelvic inflammatory diseases,PID)的相关性。方法病例选取2022年1月至2023年3月广西柳州市人民医院满足PID诊断的患者171例,根据有无生殖道感染将PID患者进一步分为单纯PID组53例、PID合并生殖道感染组118例,同期选择83例经检查未满足PID特异性诊断标准且无生殖道感染的女性为对照组。观察、比较3组间免疫抗体阳性率,探讨免疫抗体与PID之间的关系。结果单纯PID组、PID合并生殖道感染组的免疫抗体阳性率显著高于对照组,进一步观察3组间各抗体的阳性率是否存在差异,经统计分析后发现,甲状腺过氧化物酶抗体在PID合并生殖道感染组与单纯PID组的差异具有统计学意义(P<0.05)。结论甲状腺过氧化物酶抗体与生殖道感染具有一定相关性。This study was designed to evaluate the correlation between immune antibodies and pelvic inflammatory disease(PID)using retrospective analysis.Cases were selected from 171 patients who met the diagnosis of PID in Liuzhou People's Hospital of Guangxi Province from January 2022 to March 2023,and the PID patients were further divided into simple PID group(53 cases)and in PID combined with reproductive tract infection group(118 cases)according to the presence or absence of reproductive tract infections,while 83 cases of women who did not meet the specific diagnostic criteria of PID and did not have reproductive tract infections were selected as the control group during the same period.The positive rate of immune antibodies in the three groups were observed and compared to explore the relationship between immune antibodies and PID.Data showed that the positive rates of immune antibodies were significantly higher in the PID alone group and the PID combined with reproductive tract infection group than that in the control group.Furthermore,the positive rate of immune antibody TPOAb was significant difference in the PID combined with reproductive tract infection group and the PID alone group(P<0.05).In conclusion,TPOAb is closely associated with reproductive tract infections.

关 键 词：盆腔炎性疾病 免疫抗体 生殖道感染 

分 类 号：R711.33[医药卫生—妇产科学]