前庭导水管形态与梅尼埃病发生相关性研究  

Correlation Between Vestibular Aqueduct Morphology and Occurrence of Ménière's Disease

作　　者：毛秋月 杨涛[1] 邓凯[2] 彭安全[1] 邹曙光 张仪铃 张康佳 汪芹[1] MAO Qiuyue;YANG Tao;DENG Kai;PENG Anquan;ZOU Shuguang;ZHANG Yiling;ZHANG Kangjia;WANG Qin(Department of Otolaryngology Head and Neck Surgery,Xiangya Second Hospital,Central South University,Changsha 410000,China)

机构地区：[1]中南大学湘雅二医院耳鼻咽喉头颈外科,长沙410000 [2]中南大学湘雅二医院放射科

出　　处：《中华耳科学杂志》2024年第6期900-904,共5页Chinese Journal of Otology

基　　金：湖南省自然科学基金(S2022JJMSXM3132)。

摘　　要：目的研究梅尼埃病的发生与前庭导水管形态是否存在相关性,从而达到对疾病的发生及病程预测。方法回顾性纳入2018年5月2日至2021年12月15日在中南大学湘雅二医院耳鼻咽喉头颈外科确诊的梅尼埃患者,排除影像资料不全及同时存在其他外、中、内耳病变患者后共纳入120例梅尼埃患者。共纳入98例听神经瘤患者术前健侧耳为对照组。使用西门子双源force CT进行颞骨扫描,以半规管显示最大层面为标准层面,将前庭导水管形态分为0~2三个等级。0级和1级归为可显示型,2级为不显示型。应用Graphpad prism 9.3.1和SPSS25统计软件进行数据分析。结果梅尼埃患者中女性患者64名,男性患者56名,平均年龄53.18±11.81岁。前庭导水管0级患者共12人,1级患者共62人,2级患者共46人。对照组中女性患者56名,男性患者42名,平均年龄49.63±11.63岁。0级患者51例,1级患者39例,2级患者8例。对照组与MD组年龄无明显统计学差异P=0.32。MD患者组和对照组可显示型与不显示型存在明显统计学差异P<0.001。MD组健侧耳与患侧耳VA显示无明显统计学意义P=0.22。患者患耳0级、1级、2级与听力损失无明显相关性P>0.05,可显示型与不显示型与听力改变无明显相关性P>0.05。患者组听力下降程度与年龄呈正相关P=0.005。结论MD患者组与对照组前庭导水管形态存在显著差异,颞骨CT前庭导水管不可见型可能与MD发病相关。MD组双侧前庭导水管形态无明显差异,不同前庭导水管形态对MD患者听力损失无明显相关性。Objective To investigate the correlation between the occurrence of Ménière's disease(MD)and the morphology of the vestibular aqueduct(VA).Methods Data from patients with Meniere's disease(n=120,64 females and 56 males,aged 53.18±11.81 years)diagnosed in the Department of Otorhinolaryngology Head and Neck Surgery,the Second Xiangya Hospital of Central South University,from May 2,2018 to December 15,2021 were retrospectively analyzed,after excluding those with incomplete imaging data or other outer,middle and inner ear lesions.Patients with acoustic neuroma(n=98,56 females and 42 males,aged 49.63±11.63 years)were included as the control group.Temporal bone scans were acquired using Siemens dual-source force CT.The vestibular aqueduct was graded on the plane of the semicircular canal.Levels 0 and 1 were classified as displayable,and level 2 non-displayable.The Graphpad prism 9.3.1 and SPSS 25 software was used for data analysis.Results The vestibular aqueduct was graded as 0 in 12 patients,1 in 62 patients and 2 in 46 patients.Similarly,the vestibular aqueduct was graded as 0 in 51 of the control patients,1 in 39 and 2 in 8(P=0.32).There was a significant difference between the displayable and non-displayable types in both the MD patients and control patients(P<0.01).There was no correlation between display types and hearing change(P>0.05),although the degree of hearing loss in MD patient was positively correlated with age(P=0.005).Conclusion Morphology of the vestibular aqueduct shows significant differences between MD patients and non-MD patients.Non-displayable vestibular aqueducts on temporal bone CT scans may be related to pathogenesis of MD.VA levels have no significant effect on hearing changes in MD.

关 键 词：梅尼埃病 前庭导水管 CT影像 眩晕 

分 类 号：R764.33[医药卫生—耳鼻咽喉科]