氧化石墨烯表面接枝抗菌聚合物的研究  

Study on Grafting the Antibacterial Polymer on the Surface of Graphene Oxide

作　　者：李邦森 朱文雅 尹非凡 石建军 覃怀德[2] 史载锋[1] LI Bangsen;ZHU Wenya;YIN Feifan;SHI Jianjun;QIN Huaide;SHI Zaifeng(Key Laboratory of Water Pollution Treatment&Resource Reuse of Hainan Province,College of Chemistry and Chemical Engineering,Hainan Normal University,Haikou 571158,China;Rubber Research Insitute,Chinese Academy of Tropcal Agricutural Sciences,Haikou 571101,China)

机构地区：[1]海南师范大学化学与化工学院,海南省水污染治理与资源化重点实验室,海南海口571158 [2]中国热带农业科学院橡胶研究所,海南海口571101

出　　处：《海南师范大学学报（自然科学版）》2024年第3期286-291,共6页Journal of Hainan Normal University（Natural Science）

基　　金：国家自然科学基金项目(22168017);海南省自然科学基金项目(521RC1058,223RC475);海南省热带作物栽培生理学重点实验室/农业农村部儋州热带作物科学观测实验站开放课题基金项目(RRI-KLOF202303)。

摘　　要：研究了一种制备两性离子聚合物修饰的抗菌氧化石墨烯(GO-PSBMA)的方法。基于氧化石墨烯(GO)表面含有大量的-OH,采用酯化反应制备了具有大量溴引发位点的GO(GO-Br)。使用甲基丙烯酸磺基甜菜碱(SBMA)作为聚合单体,通过表面引发的原子转移自由基聚合(SIATRP)在GO-Br表面进行聚合。用聚合物改性的GO对大肠杆菌表现出99.99%的抗菌活性。本研究有效地建立了对氧化石墨烯的新型聚合物改性方法,赋予其优异的抗菌性能。A method for preparing antibacterial graphite oxide(GO-PSBMA)modified by zwitter-ionic polymer brush was studied.GO(GO-Br)with a large number of bromine initiation sites was prepared by esterification based on the large amount of-OH on the surface of graphene oxide(GO).Methacrylate sulfobetaine(SBMA)was used as the polymerization monomer and polymerized on the surface of GO-Br by surface-initiated atomic transfer radical polymerization(SI-ATRP).GO modified with polymer brush showed 99.99%antibacterial activity against E.coli.A novel polymer modification method for graphene oxide was effectively established,which endows it with excellent antibacterial properties.

关 键 词：氧化石墨烯 表面接枝 抗菌聚合物 

分 类 号：O634[理学—高分子化学]