非急性症状性颅内大动脉闭塞介入开通治疗的效果  

Clinical effect of interventional recanalization therapy in treatment of non-acute symptomatic intracranial large artery occlusion

作　　者：杨占辉 王鹏 孟芳 李青菊 付广印 徐丹 YANG Zhanhui;WANG Peng;MENG Fang;LI Qingju;FU Guangyin;XU Dan(Intervention Department of Hengshui People’s Hospital,Hengshui 053000,China)

机构地区：[1]衡水市人民医院介入科,河北衡水053000 [2]衡水市第六人民医院影像科

出　　处：《青岛大学学报（医学版）》2024年第5期763-766,共4页Journal of Qingdao University(Medical Sciences)

基　　金：衡水市科技计划项目(2021014097Z)。

摘　　要：目的探究非急性症状性颅内大动脉闭塞介入开通治疗的临床效果。方法选取2021年8月-2023年8月衡水市人民医院、衡水市第六人民医院、河北医科大学第二医院、河北省人民医院收治的非急性症状性颅内大动脉闭塞病人200例为研究对象,以药物内科治疗病人100例为对照组,介入开通治疗病人100例为治疗组,比较两组的疗效差异。结果术后治疗组血管再通率为98%。每组治疗前后不同时间的美国国立卫生研究院卒中量表(NIHSS)评分差异有统计学意义(F=101.984、971.202,P<0.05)。相较于治疗前,治疗1、3、6个月后两组NIHSS评分均显著降低(P<0.05),且治疗组均低于对照组(F=5.782~8.497,P<0.05)。与对照组比较,治疗组术后3、6个月改良Rankin量表评分≤2分者的比例更高(χ^(2)=4.348、9.072,P<0.05),复发率更低(χ^(2)=3.097,P<0.05)。结论介入开通治疗非急性症状性颅内大动脉闭塞具有较高的血管再通率,可以有效改善病人神经功能和预后。Objective To investigate the clinical effect of interventional recanalization therapy in the treatment of non-acute symptomatic intracranial large artery occlusion.Methods A total of 200 patients with non-acute symptomatic intracranial large artery occlusion who were admitted to Hengshui People’s Hospital,The Sixth People’s Hospital of Hengshui,The Second Hospital of Hebei Medical University,and Hebei General Hospital from August 2021 to August 2023 were enrolled as subjects,among whom 100 patients treated with medication were enrolled as control group and 100 patients treated with interventional recanalization therapy were enrolled as treatment group.Treatment outcome was compared between the two groups.Results The treatment group achieved a vascular recanalization rate of 98%after surgery.There was a significant difference in National Institutes of Health Stroke Scale(NIHSS)score across different times before and after treatment in each group(F=101.984,971.202,P<0.05).Both groups had a significant reduction in NIHSS score after 1,3,and 6 months of treatment(P<0.05),and the treatment group had a significantly lower score than the control group(F=5.782-8.497,P<0.05).Compared with the control group,the treatment group had a significantly higher proportion of patients with a modified Rankin Scale score of≤2 at 3 and 6 months after surgery(χ^(2)=4.348,9.072,P<0.05)and a significantly lower recurrence rate(χ^(2)=3.097,P<0.05).Conclusion Interventio-nal recanalization therapy for non-acute symptomatic intracranial large artery occlusion can achieve a relatively high vascular recanalization rate and effectively improve the neurological function and prognosis of patients.

关 键 词：动脉闭塞性疾病 颅内动脉疾病 放射学 介入性 治疗结果 

分 类 号：R543.5[医药卫生—心血管疾病] R81[医药卫生—内科学]