慢性呼吸系统疾病管理的现状和展望  

Current status and prospects of management of chronic respiratory diseases

作　　者：朱衣兴 常德 Zhu Yixing;Chang De(Department of Respiratory and Critical Care Medicine,Eighth Medical Center,Chinese PLA General Hospital,Beijing 100026,China;General Hospital Graduate School,Chinese PLA General Hospital,Beijing 100853,China;Department of Respiratory and Critical Care Seventh Medical Center,Chinese PLA General Hospital,Beijing 100091,China)

机构地区：[1]中国人民解放军总医院第八医学中心呼吸与危重症医学部,北京100026 [2]中国人民解放军总医院研究生院,北京100853 [3]中国人民解放军总医院第七医学中心呼吸与危重症医学科,北京100091

出　　处：《结核与肺部疾病杂志》2024年第6期567-572,共6页Journal of Tuberculosis and Lung Disease

基　　金：国家“十四五”重点研发计划青年科学家项目(2021YFC2302300);部队“三才一队”人才工程计划(2021-439);军队高层次科技创新人才工程(2022-QN07351);解放军总医院“3+1”创新人才建设工程学科拔尖人才(20230315);北京市科技新星计划交叉学科合作课题(20220484197)。

摘　　要：慢性呼吸系统疾病是一组起病隐匿、病程迁延的非传染性疾病,具有病因复杂、治疗费用高昂及预后不良等特点。本综述系统分析了慢性阻塞性肺疾病、哮喘、肺癌及间质性肺病等主要类型的流行病学、病理生理机制及临床管理策略。强调了早期诊断的重要性,探讨了治疗依从性、个体化治疗策略及资源配置等管理挑战,并展望了靶向治疗、基因治疗、数字健康技术等新兴治疗手段的应用前景,旨在为临床医生提供全面的疾病管理视角。Chronic respiratory diseases are a group of non-communicable diseases characterized by insidious onset and protracted course,with complex etiology,high treatment costs,and poor prognosis.This review systematically analyzes the epidemiology,pathophysiological mechanisms,and clinical management strategies of major types of chronic respiratory diseases such as chronic obstructive pulmonary disease,asthma,lung cancer,and interstitial lung diseases.The paper highlights the importance of early diagnosis,discusses management challenges such as treatment adherence,individualized treatment strategies and resource allocation,and looks into the future application prospects of emerging therapeutic approaches like targeted therapy,gene therapy,and digital health technologies,aiming to provide clinicians a comprehensive perspective on disease management.

关 键 词：肺疾病 慢性阻塞性 哮喘 肺肿瘤 肺疾病 间质性 流行病学研究特征(主题) 卫生服务管理 

分 类 号：R714.253[医药卫生—妇产科学]