针刺治疗卒中后中枢性疼痛作用机制研究进展  

Progress in the Mechanism of Acupuncture in the Treatment of Central Post-stroke Pain

作　　者：白洁如 王宇[1] 张伊菲 张安珍 王璐[2] 李季[2] 张立[1,2] BAI Jieru;WANG Yu;ZHANG Yifei;ZHANG Anzhen;WANG Lu;LI Ji;ZHANG Li(Heilongjiang University of Chinese Medicine,Harbin 150040,Heilongjiang,China;The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150001,Heilongjiang,China)

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040 [2]黑龙江中医药大学附属第二医院,黑龙江哈尔滨150001

出　　处：《辽宁中医药大学学报》2024年第12期209-213,共5页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：哈尔滨市科技计划自筹经费项目(2022ZCZJNS070)。

摘　　要：卒中后中枢性疼痛(central poststroke pain,CPSP)是卒中后常见但易被忽视的疼痛综合征,临床病证常导致患者睡眠质量下降,损害其生活质量,甚至引起情绪障碍。针刺治疗适应证广、疗效确切且安全无不良反应,临床应用价值高,值得广泛推广。近几年针刺治疗CPSP的文献多对其针刺手法、治法进行总结,但从针灸对CPSP治疗机制角度进行总结的比较少见。该文通过对近年来针刺疗法治疗CPSP的相关机制研究概况进行总结,从针刺疗法对神经纤维、信号分子、神经递质、炎症反应、突触可塑性、细胞自噬等方面的作用分析针刺疗法治疗CPSP的可能机制,并对其进行综述,以期为理论研究和临床运用提供参考。Central post-stroke pain(CPSP)is one of the most common but overlooked sequelae after stroke that can reduce sleep quality,impair quality of life,and cause mood disorders.Clinical symptoms often lead to decreased sleep quality,impair quality of life,and even cause emotional disorders.Acupuncture has a wide range of indications,accurate efficacy,safety,non-toxic side effects,and high clinical application value.It is worthy of widespread promotion.In recent years,most of the literatures about acupuncture therapy of CPSP have summarized acupuncture techniques and treatment methods,but the summary from the perspective of acupuncture therapy mechanism of CPSP is relatively rare.In this paper,we summarized the research on the mechanism of acupuncture therapy in CPSP,and analyzed the possible mechanism of acupuncture therapy in CPSP from the effects of acupuncture therapy on nerve fibers,signaling molecules,neurotransmitters,inflammatory response,synaptic plasticity,autophagy and so on,and reviews it.In order to provide reference for theoretical research and clinical application.

关 键 词：针刺疗法 卒中后中枢性疼痛 机制研究 

分 类 号：R245.3[医药卫生—针灸推拿学] R255.2[医药卫生—中医临床基础] R743.3[医药卫生—中医学]