用氩氦冷冻消融术治疗犬口腔黑色素瘤的研究  

Treatment of Canine Oral Melanoma by Argon-helium Cryoablation

作　　者：白雪瑞 董颖波 李卓群 胡红 战晓燕 李尚同 王金福[1] 刘艳海 BAI Xuerui;DONG Yinbo;LI Zhuoqun;HU Hong;ZHAN Xiaoyan;LI Shangtong;WANG Jinfu;LIU Yanhai(Department of Animal Science and Technology,Shanghai Vocational and Technical College of Agriculture and Forestry,Shanghai 201699,China;Department of Animal Science and Technology,Shanghai Agricultural School,Shanghai 201600,China;AMC Hexi Central Animal Hospital,Nanjing,Jiangsu 210000,China;Animal Medical College of Nanjing Agricultural University,Nanjing,Jiangsu 210095,China)

机构地区：[1]上海农林职业技术学院动物科学技术系,上海201699 [2]上海市农业学校动物科学技术系,上海201600 [3]AMC河西中心动物医院,江苏南京210000 [4]南京农业大学动物医学院,江苏南京210095

出　　处：《畜牧兽医杂志》2024年第6期63-67,共5页Journal of Animal Science and Veterinary Medicine

基　　金：上海农林职业技术学院科研课题(KY2-0000-20-10)。

摘　　要：口腔黑色素瘤是犬最常见的口腔恶性肿瘤,易发于老年犬。本病例通过采用新型氩氦冷冻消融术治疗老年犬Ⅱ型口腔黑色素瘤,结果显示,术后20d,患处显示瘤样软组织显著缩小,炎性分泌物消失;术后3个月,瘤样软组织基本消退,伤口愈合良好;术后9个月,患犬未发生肿瘤复发或转移。结果表明,氩氦刀冷冻消融术具有安全有效的特点,可作为老年犬口腔黑色素瘤的新型治疗手段,值得在兽医临床推广和应用。Oral melanomas are the most common form of oral malignancy with a relatively poor prognosis in dogs,and prone to older dogs.For older dogs,due to their low immune function,the treatment is more difficult,and traditional surgery is not effective in the treatment of oral melanoma in dogs.Therefore,it is extremely important to explore a novel treatment for oral melanoma in older dogs.In this case,a novel argon-helium cryoablation was used to treat type II oral melanoma in an elderly dog.The results showed that the tumor-like soft tissue was significantly reduced and the inflammatory secretions disappeared 20 days after surgery;the tumor-like soft tissue basically subsided and the wound healed well 3 months after surgery;and no tumor recurrence or metastasis occurred 9 months after surgery.It indicated that novel argon-helium cryoablation is safe and effective for the treatment of canine oral melanoma in older dogs,which is worth popularizing in veterinary clinic.

关 键 词：氩氦刀 口腔黑色素瘤 老龄犬 冷冻消融术 

分 类 号：S857.14[农业科学—临床兽医学]