Voluntary walking related joint movement training with targeted epidural electrical stimulation enabled neural recovery for individuals with spinal cord injury  

靶向硬膜外电刺激结合自主关节运动恢复训练辅助脊髓损伤患者的神经修复

作　　者：Xi Zhang Yang Lu Boyang Zhang Hongda Li Qingyu Yao Junhong Lim Yunyue Wei Kaibo He Chenhui Zuo Yanan Sui Bozhi Ma Mingshan Ran Yu Pan Guihuai Wang Luming Li 张熹;陆洋;张博扬;李洪达;姚庆宇;林峻弘;韦云岳;何凯波;左晨辉;睦亚楠;马伯志;冉明山;潘钰;王贵怀;李路明

机构地区：[1]National Engineering Research Center of Neuromodulation,Tsinghua University,Beijing 100084,China [2]Department of Neurosurgery,Beijing Tsinghua Changgung Hospital,School of Clinical Medicine,Tsinghua University,Beijing 102218,China [3]School of Aerospace Engineering,Tsinghua University,Beijing 100084,China [4]Department of Rehabilitation Medicine,Peking University Shougang Hospital,Beijing 100144,China [5]IDG/McGovern Institute for Brain Research at Tsinghua University,Beijing 100084,China [6]Changping Laboratory,Beijing 102206,China [7]Department of Rehabilitation Medicine,Beijing Tsinghua Changgung Hospital,School of Clinical Medicine,Tsinghua University,Beijing 102218,China

出　　处：《Science Bulletin》2024年第22期3507-3511,共5页科学通报（英文版）

基　　金：supported by the Beijing Nova Program(2021B00003292 and 20220484216);the National Key Research and Development Project of China(2023YFC2415600)。

摘　　要：Spinal cord injury(SCI)poses a substantial medical and social challenge,frequently leading to partial or complete loss of motor function below the site of injury[1].The disruption of descending neural pathways and the consequent loss of neural connectivity impair voluntary movement and interfere with sensory and autonomic functions.Traditional therapeutic strategies have primarily centered on compensatory methods,helping individuals with SCI adapt to their impairments[2].However,recent advances in neurorehabilitation are shifting the paradigm toward restorative treatments that seek to re-establish neural connections and promote functional recovery.

关 键 词：stimulation NEURAL injury 

分 类 号：R651.2[医药卫生—外科学]