基于透射扫描的PET/MR数据衰减校正方法  

PET/MR attenuation correction method based on transmission scan

作　　者：范胜男 郭兴照 马卫东[1] 邓君[1] 邓磊 刘小平 FAN Shengnan;GUO Xingzhao;MA Weidong;DENG Jun;DENG Lei;LIU Xiaoping(National Institute for Radiological Protection,Chinese Center for Disease Control and Prevention,Beijing 100088 China;Qingdao municipal hospital,Qingdao 266071 China;Institute Of Occupational Medicine Of Jiangxi,Nanchang 330006 China;Beijing Topgrade Medical Equipment Co.,LTD,Beijing 102600 China)

机构地区：[1]中国疾病预防控制中心辐射防护与核安全医学所,北京100088 [2]青岛市市立医院,山东青岛266071 [3]江西省职业病防治研究院,江西南昌330006 [4]北京大基康明医疗设备有限公司,北京102600

出　　处：《中国辐射卫生》2024年第5期499-504,共6页Chinese Journal of Radiological Health

摘　　要：目的基于透射扫描,提出一种用于PET/MR中PET数据衰减校正方法,提高图像质量,以期提高诊断准确性和病灶定位精确度。方法本研究使用GB/T 18988.1—2013标准中的头部体模作为实验模型。该头部体模包含了3根可灵活取出的直径为50 mm的圆柱形插入物,分别填充空气、水和实心聚四氟乙烯。基于透射扫描,计算衰减校正因子并做了分析与讨论。结果当slice=33,theta=0时,符合线通过模型中轴线的衰减校正因子最大,约为7.5。衰减校正因子的空间分布清楚地显示了空气插入和实心聚四氟乙烯插入的位置,表明用透射扫描数据计算的衰减校正因子是比较准确的。在临床验证实验中,基于透射扫描的衰减校正方法,可使图像质量得到明显改善,有较好的衰减校正效果。结论本研究基于透射扫描,对PET/MR中PET数据衰减校正方法进行了研究,可较好地改善图像质量。在今后的工作中,将进一步研究和优化PET/MR数据衰减校正方法,助力临床应用。Objective To propose a method for correcting the attenuation of positron emission tomography(PET)data in PET/magnetic resonance(MR)based on transmission scan,and to improve image quality,diagnostic accuracy,and lesion location accuracy.Methods In this study,the head phantom in the national standard GB/T 18988.1—2013 was used as the experimental model.The head phantom contained three 50 mm diameter cylindrical inserts filled with air,water,and solid teflon.The attenuation correction coefficients were calculated and analyzed based on transmission scan.Results With slice=33 and theta=0,the attenuation correction coefficient was the largest(about 7.5)when the coincidence line passed through the axis of the phantom.The spatial distribution of the attenuation correction coefficients clearly showed the posi-tions of air insert and teflon insert,indicating that the attenuation correction coefficients calculated from transmission scan data were accurate.In the clinical verification experiment,the attenuation correction method based on transmission scan sig-nificantly improved the image quality and showed efficient attenuation correction.Conclusion This paper studied the at-tenuation correction method for PET data in PET/MR based on transmission scan.This method can improve the image qual-ity.In the future work,the attenuation correction method of PET/MR will be further studied and optimized to facilitate clin-ical applications.

关 键 词：正电子发射断层成像 磁共振成像 衰减校正 透射扫描 

分 类 号：R445[医药卫生—影像医学与核医学]