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作 者:雷剑飞 覃卫常 韦定周 杨启升 王丽盛 龙明进 LEI Jianfei;QIN Weichang;WEI Dingzhou;YANG Qisheng;WANG Lisheng;LONG Mingjin(Spine and Joint Surgery Department,the People's Hospital of Rong'an County,Liuzhou 545400,China)
机构地区:[1]广西融安县人民医院脊柱关节外科,广西柳州545400
出 处:《临床医学研究与实践》2024年第33期38-41,共4页Clinical Research and Practice
基 金:广西壮族自治区卫生健康委员会自筹经费科研课题(No.Z20211172)。
摘 要:目的探讨经皮椎间孔镜下病灶清除置管引流术治疗胸腰椎结核的效果。方法选取60例胸腰椎结核患者作为研究对象,采用随机数字表法将其分为对照组和观察组,各30例。两组均接受常规药物治疗,对照组实施开放手术,观察组实施经皮椎间孔镜下病灶清除置管引流术。比较两组的治疗效果。结果观察组的治疗总有效率高于对照组(P<0.05)。术后1个月,两组的Oswestry功能障碍指数(ODI)、视觉模拟评分法(VAS)评分均降低,且观察组低于对照组(P<0.05)。术后1个月,观察组的红细胞沉降率(ESR)、C反应蛋白(CRP)水平低于对照组(P<0.05)。术后1个月,观察组的白蛋白(ALB)、血红蛋白(Hb)水平高于对照组(P<0.05)。观察组的并发症总发生率低于对照组(P<0.05)。结论经皮椎间孔镜下病灶清除置管引流术治疗胸腰椎结核患者效果显著,可有效清除结核病灶,减轻炎症反应及疼痛程度,改善腰椎功能及营养状态。Objective To explore the effect of percutaneous transforaminal endoscopic debridement and catheter drainage in the treatment of thoracolumbar tuberculosis.Methods A total of 60 patients with thoracolumbar tuberculosis were selected as the research objects and divided into control group and observation group by random number table method,with 30 cases in each group.Both groups received routine drug treatment.The control group underwent open surgery,and the observation group underwent percutaneous transforaminal endoscopic debridement and catheter drainage.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).One month after operation,the Oswestry Disability Index(ODI)and Visual Analogue Score(VAS)scores of the two groups decreased,and those in the observation group were lower than the control group(P<0.05).One month after operation,the erythrocyte sedimentation rate(ESR)and C-reactive protein(CRP)level in the observation group were lower than those in the control group(P<0.05).One month after operation,the levels of albumin(ALB)and hemoglobin(Hb)in the observation group were higher than those in the control group(P<0.05).The total incidence of complications in the observation group was lower than that in the control group(P<0.05).Conclusion Percutaneous transforaminal endoscopic debridement and catheter drainage for patients with thoracolumbar tuberculosis has a significant effect,which can effectively remove tuberculosis lesions,reduce inflammation and pain,and improve lumbar function and nutritional status.
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