39例局部复发肺癌患者再程放疗疗效观察  

Observation on the effect of re-irradiation for 39 local recurrent lung cancer patients

作　　者：张建鑫 ZHANG Jianxin(Department of Oncology,Shanting District People's Hospital of Zaozhuang City,Zaozhuang,Shandong 277200,China)

机构地区：[1]枣庄市山亭区人民医院肿瘤科,山东枣庄277200

出　　处：《影像研究与医学应用》2024年第23期28-31,共4页Journal of Imaging Research and Medical Applications

摘　　要：目的:评估局部复发肺癌患者再程放疗后的疗效及安全性。方法:回顾性分析2013年10月—2019年2月枣庄市山亭区人民医院收治的39例肺癌复并且再次接受放疗的患者临床资料。采用Kaplan-Meier统计法计算生存期(OS),并根据CTCAE4.0评分标准对放疗后毒性进行评分。单因素和多因素分析影响OS的预后因素。结果:所有患者的中位OS为18.4个月,中位局部控制时间为7.9个月。再程照射体积是OS的主要影响因素。结论:胸部再程放疗在延长肺癌复发患者的生存期方面发挥着重要作用,尤其对较小体积复发肿瘤效果更为显著。Objective To evaluate the efficacy and safety of re-radiotherapy in patients with local recurrent lung cancer.Methods The clinical data of 39 patients with lung cancer who received radiotherapy again in Shanting District People's Hospital of Zaozhuang City from October 2013 to February 2019 were retrospectively analyzed.Overall survival(OS)were calculated using Kaplan–Meier statistics and post-RT toxicity data was scored following CTCAE 4.0.Univariate and multivariate analyses were used to analyze prognostic factors affecting OS.Results The median OS for all patients was 18.4 months and the median time to local control was 7.9 months.The volume of re-irradiation is the main influencing factor of OS.Conclusion Thoracic re-radiotherapy plays an important role in prolonging the survival of patients with recurrent lung cancer,especially in patients with small tumor volume at recurrence.

关 键 词：肺癌 局部复发 再程放疗 

分 类 号：R445[医药卫生—影像医学与核医学]