甲状腺癌患者超声造影参数与淋巴结转移的关系探讨  

Exploration of the relationship between contrast-enhanced ultrasound parameters and lymph node metastasis in patients with thyroid cancer

作　　者：赵颖[1] 张艳[1] ZHAO Ying;ZHANG Yan(Department of Ultrasound,Peixian People's Hospital,Xuzhou,Jiangsu 221600,China)

机构地区：[1]沛县人民医院超声科,江苏徐州221600

出　　处：《影像研究与医学应用》2024年第23期35-37,41,共4页Journal of Imaging Research and Medical Applications

摘　　要：目的:分析甲状腺癌(TC)患者超声造影(CEUS)参数与淋巴结转移的关系。方法:选取2021年1月—2024年5月沛县人民医院收治的135例TC患者为研究对象,以病理诊断结果提示是否发生淋巴结转移,将患者分为转移组71例与无转移组64例。均行CEUS检查,对比两组超声造影特征及定量参数,并分析CEUS参数与甲状腺癌淋巴结转移的关系。结果:两组CEUS灌注特征比较差异无统计学意义(P>0.05);转移组肿瘤直径大于无转移组,差异有统计学意义(P<0.05);两组上升时间(RT)、上升斜率(WIS)、峰值降半时间(TPH)及达峰时间(TTP)水平比较,差异无统计学意义(P>0.05);转移组平均渡越时间(MTT)低于无转移组,峰值强度(PI)高于无转移组,差异有统计学意义(P<0.05);Pearson相关性分析显示,MTT与甲状腺癌患者淋巴结转移呈负相关,PI与甲状腺癌患者淋巴结转移呈正相关(P<0.05)。结论:TC患者淋巴结转移与癌结节大小、CEUS参数MTT及PI有关,通过测定CEUS参数可准确评估淋巴结转移情况,以指导临床治疗。Objective To analyze the relationship between contrast-enhanced ultrasound(CEUS)parameters and lymph node metastasis in thyroid cancer(TC)patients.Methods A total of 135 TC patients admitted to Peixian People's Hospital from January 2021 to May 2024 were selected as the research subjects.Pathological diagnosis results were used to indicate whether lymph node metastasis had occurred.The patients were divided into a metastasis group of 71 cases and a non-metastasis group of 64 cases.Those enrolled in the group underwent CEUS examination to determine quantitative parameters.The ultrasonographic features and quantitative parameters of the two groups were compared,and the relationship between CEUS parameters and lymph node metastasis of thyroid cancer was analyzed.Results There was no statistically significant difference in the perfusion characteristics between the two groups of CEUS(P>0.05);the tumor diameter in the metastatic group was larger than that in the non-metastatic group,and the difference was statistically significant(P<0.05);there was no statistically significant difference in the levels of RT,WIS,TPH and TTP between the two groups(P>0.05);the MTT of the metastasis group was lower than that of the non-metastasis group,and the PI was higher than that of the non-metastasis group,with statistically significant differences(P<0.05);and Pearson's correlation analysis showed that MTT was negatively correlated with lymph node metastasis in thyroid cancer patients,and PI was positively correlated with lymph node metastasis in thyroid cancer patients(P<0.05).Conclusion Lymph node metastasis in TC patients is related to the size of cancer nodes,CEUS parameters MTT and PI,and lymph node metastasis can be accurately assessed by determining CEUS parameters to guide clinical treatment.

关 键 词：甲状腺癌 淋巴结转移 超声造影 达峰时间 峰值强度 相关性 

分 类 号：R445.1[医药卫生—影像医学与核医学]