32家儿童医院真菌实验室建设和能力基线调研报告  

Report on the construction and capacity baseline survey of fungal laboratories in 32 children's hospitals

作　　者：陈运生[1] 叶炳均 杨文航[2,3,4] 苏琪茹 麻晓鹏 王瑶[2,3,4] 林丽开[4,5] 徐英春 CHEN Yunsheng;YE Bingjun;YANG Wenhang;SU Qiru;MA Xiaopeng;WANG Yao;LIN Likai;XU Yingchun(Department of Clinical Laboratory,Shenzhen Children's Hospital,Shenzhen 518038,China;Department of Clinical Laboratory,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China;Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Disease,Beijing 100730,China;National center of China Fungal Diseases Surveillance System,Beijing,China;Wuhan University Hospital Management Institute,Wuhan 430071,China)

机构地区：[1]深圳市儿童医院检验科,深圳518038 [2]中国医学科学院北京协和医院检验科,北京100730 [3]侵袭性真菌病机制研究与精准诊断北京市重点实验室,北京100730 [4]全国真菌病监测网国家中心,北京100730 [5]武汉大学医院管理研究所,武汉430071

出　　处：《中国真菌学杂志》2024年第5期473-479,共7页Chinese Journal of Mycology

摘　　要：目的全面了解我国儿童医院、妇儿医院及部分综合医院儿科等单位真菌实验室的建设情况。方法国家卫生健康委全国真菌病监测网开展了“儿童医院真菌实验室建设和能力基线调研”[国卫医函〔2021〕73号],本研究基于全国真菌病监测网数据填报系统,对我国儿童医院、妇儿医院及部分综合医院儿科等2022年度在真菌实验室基础建设、硬件投入、人员配备、技术能力、临床服务能力及真菌病相关科研教学能力等方面的情况进行在线调研,并对调研结果进行了分析。结果参与调研的32家医院真菌实验室基础设施基本满足临床真菌检验需求,真菌检验技术人员储备和技术能力有待于进一步提高,部分真菌检验项目开展率较低,如六胺银染色(37.5%)、真菌荧光染色(53.1%)、丝状真菌抗真菌药物敏感性试验(12.5%)等。结论各实验室应进一步加强真菌检验能力建设,开展多样化真菌检验项目,尤其提高对丝状真菌的诊断和检测能力,建立规范化的真菌病原学临床诊断体系,为提高临床儿童真菌病诊疗能力提供坚实的后盾。Objective In order to comprehensively understand the construction of fungal laboratories in children's hospitals,women's and children's hospitals,and pediatric units in some general hospitals in China,the China Fungal Disease Surveillance System(CFDSS)of the National Health Commission has carried out a"baseline survey on the construction and capacity of fungal laboratories in children's hospitals"[National Health Medical Letter(2021)No.73].Method An online survey was conducted on the infrastructure construction,hardware investment,staffing,technical ability,clinical service ability and mycosis related research and teaching ability of pediatric departments in children's hospitals,women's and children's hospitals and some general hospitals in 2022,and the results were statistically analyzed in this paper.Result The survey showed that the infrastructure of the 32 hospitals participating in the survey basically met the needs of clinical fungal testing,and the reserve and technical ability of fungal testing technicians needed to be further improved.The implementation rates of some fungal testing projects were low,such as silver hexamine staining(37.5%),fungal fluorescence staining(53.1%),antifungal susceptibility test of filamentous fungi(12.5%)and so on.Conclusion It is suggested that all laboratories should further strengthen the capacity building of fungal examination,carry out diversified fungal examination projects,especially improve the diagnosis and detection ability of filamentous fungi,and establish a standardized clinical diagnosis system of fungal etiology,so as to provide a solid support for improving the diagnosis and treatment ability of clinical children with fungal diseases.

关 键 词：儿童 真菌实验室 调查分析 基线调研 

分 类 号：R446.5[医药卫生—诊断学]